Clinical Implications of Age in Differentiated Thyroid Cancer: Comparison of Clinical Outcomes between Children and Young Adults
Table 9
Subanalysis of clinicopathological characteristics of patients with tumor size of 2 to 4 cm.
<20 years (n = 47)
20–29 years (n = 187)
30–39 years (n = 367)
value
Age (years)
15.6 ± 3.7
25.9 ± 2.6
34.3 ± 2.8
<0.001
Male : female
1 : 4.9
1 : 5.9
1 : 4.2
0.374
Male
8 (17.0%)
27 (14.4%)
70 (19.1%)
Female
39 (83.0%)
160 (85.6%)
297 (80.9%)
Tumor size (cm)
2.8 ± 0.7
2.7 ± 0.6
2.6 ± 0.6
0.321
Type of carcinoma
0.859
PTC
45 (95.7%)
178 (95.2%)
352 (95.9%)
FTC
2 (4.3%)
9 (4.8%)
15 (4.1%)
Multifocality
15 (31.9%)
42 (22.5%)
98 (26.7%)
0.385
Bilaterality
13 (27.7%)
30 (16.0%)
73 (19.9%)
0.231
ETE
24 (51.1%)
92 (49.2%)
192 (52.3%)
0.572
T stage
0.357
T2
20 (42.6%)
93 (49.7%)
172 (46.9%)
T3
23 (48.9%)
85 (45.5%)
175 (47.7%)
T4
4 (8.5%)
9 (4.8%)
20 (5.4%)
N stage
0.006
N0
10 (21.3%)
67 (35.8%)
114 (31.1%)
N1a
14 (29.8%)
62 (33.2%)
154 (42.0%)
N1b
23 (48.9%)
58 (31.0%)
99 (26.9%)
M stage
0.260
M1
2 (4.3%)
0 (0%)
4 (1.1%)
Recurrence
12 (25.5%)
31 (16.6%)
35 (9.5%)
0.001
Data are expressed as patient’s number (%) or mean ± SD. A statistically significant difference was defined as . PTC, papillary thyroid carcinoma; FTC, follicular thyroid carcinoma; ETE, extrathyroidal extension; T, tumor; N, node; M, metastasis.
