Oleic Acid and Succinic Acid Synergistically Mitigate Symptoms of Type 2 Diabetes in Streptozotocin-Induced Diabetic Rats

Table 1

Variation in serum insulin, glucagon, and insulin resistance in treated and untreated diabetic and nondiabetic Sprague Dawley rats.

	NC	NT	DC	DGLIB	DT
Serum insulin levels (ng/mL)	0.49 ± 0.06^a	0.44 ± 0.06^a	0.39 ± 0.05^a	0.53 ± 0.05^a	0.46 ± 0.05^a
Serum glucagon levels (pg/mL)	17.29 ± 4.80^a	26.66 ± 5.09^a	55.50 ± 10.93^b	40.12 ± 12.55^ab	25.16 ± 6.82^a
G/I × 10^3	1.638 ± 0.246^a	1.831 ± 0.197^a	3.728 ± 0.556^b	1.288 ± 0.138^a	1.951 ± 0.263^a
QUICKI	0.336 ± 0.006^a	0.344 ± 0.002^a	0.313 ± 0.004^b	0.334 ± 0.004^a	0.334 ± 0.002^a

Data are expressed as mean ± standard error of the mean and analysed by Tukey post hoc test. NC: normal control, NT: normal treatment, DC: diabetic control, DT: diabetic treatment, and DGlib: diabetic glibenclamide group, where the letters represent the following: a, statistically significant differences when compared with the values in the same row with superscripts b; b, statistically significant differences when compared with the values in the same row with superscripts a. Significant difference is considered at .