Research Article

Changes in Cross-Sectional Area of the Median Nerve and Body Composition Parameters after Treatment of Acromegaly: 1 year Follow-Up

Table 2

Comparison of biochemical characteristics, CSA of the median nerve, and body composition parameters in acromegalic patients at baseline and 1 year after treatment of acromegaly.

CharacteristicsAt diagnosis1 year follow-up value

GH (ng/ml)6.50 [3.03–10.79]0.55 [0.34–1.29]<0.001
IGF-1 (ng/ml)526 [372–686]210 [169–263]<0.001
BMI (kg/m2)30.8 [25.0–34.1]30.2 [26.2–34.5]Ns
CSA of the median nerve(mm2)13.1 [12.2–14.9]11.6 [10.2–13.1]<0.001
Fat mass (kg)30.1 [23.1–36.9]30.7 [26.9–39.4]0.038
Lean mass (kg)60.4 [47.1–74.9]60.9 [47.1–73.2]0.032

Data are presented as median (standard interquartile range). The level of significance was set at . GH: growth hormone, IGF-1: insulin-like-growth factor 1, BMI: body mass index, and CSA: cross-sectional area.