Central Diabetes Insipidus in Children and Adolescents: Twenty-Six Year Experience from a Single Centre

Table 1

Aetiology and age at diagnosis of central diabetes insipidus in 138 patients.

Diagnosis	No. of patients (%)	Median age at diagnosis (years)
Craniopharyngioma and/or its treatment	44 (31.6)	10.7
Germinoma and/or its treatment	15 (11.5)	10.5
Postneurosurgery (indication other than craniopharyngioma and germinoma)	20 (14.4)	9.0
Acute CNS insult
CNS infection	12 (8.6)	0.08
Head trauma	8 (5.8)	2.1
Vascular lesion	8 (5.8)	0.4
Hypoxic ischaemic event	5 (3.6)	1.8
CNS malformation	14 (10.1)	0.1
Langerhans cell histiocytosis	5 (3.6)	5.0
Familial	2 (1.4)	10
Idiopathic	5 (3.6)	6.0