Insulin Autoimmune Syndrome: A Systematic Review

Table 2

IAS-related drugs and the number of cases (N).

Related drugs	N
Methimazole	170 (21.38%)
Alpha lipoic acid	51 (6.42%)
Clopidogrel	8 (1.01%)
Esomeprazole	1 (0.13%)
Captopril	8 (1.01%)
Insulin and its analogues	20 (2.52%)
Sulfhydryl-containing health products	2 (0.25%)
Insulin aspartate 30	27 (3.40%)
Insulin glargine	2 (0.25%)
Glucosamine sulfate-containing drugs	1 (0.13%)
Insulin lispro	3 (0.38%)
131I therapy	2 (0.25%)
Mercaptan	2 (0.25%)
Tiopronin	54 (6.80%)
Zinc protamine recombinant human insulin	11 (1.38%)
Acetylcysteine	1 (0.13%)
Penicillamine	2 (0.25%)
Carbimazole	3 (0.38%)
Propylthiouracil	3 (0.38%)
Penicillin G	1 (0.13%)
Ganshulin 50R	2 (0.25%)
Coenzyme Q10	1 (0.13%)
Omeprazole	1 (0.13%)
Human serum albumin	1 (0.13%)
Antituberculosis treatment	2 (0.25%)
Loxoprofen sodium	2 (0.25%)
Insulin glulisine	1 (0.13%)
Pantoprazole	1 (0.13%)
Methionine-containing supplements	1 (0.13%)
Imipenem	1 (0.13%)
Azathioprine	1 (0.13%)
Glimepiride	1 (0.13%)
Glutathione	8 (1.01%)
Gold thioglucoce	1 (0.13%)
Acegratone	1 (0.13%)
Interferon-alfa	1 (0.13%)
Gliclazide	1 (0.13%)
Unknown or no	399 (50.19%)
Total	795