Research Article

Effect of Teriparatide on Bone Mineral Density and Bone Markers in Real-Life: Argentine Experience

Table 2

Changes in biochemical parameters during treatment with teriparatide.

Basal6 months12 months18 months24 months

PTH (pg/mL)44.5 ± 18.9 (n = 168)36.5 ± 19.2(n = 62)37.5 ± 19.0(n = 79)38.8 ± 18.6 (n = 35)42.9 ± 19.6 (n = 39)
Serum calcium (mg/dL)9.5 ± 0.5 (n = 245)9.8 ± 0.5(n = 168)9.6 ± 0.5(n = 198)9.7 ± 0.5(n = 103)9.7 ± 0.5(n = 72)
Urinary calcium (mg/24 h)149.8 ± 66.1 (n = 191)199.7 ± 106.2(n = 110)184.3 ± 117.5(n = 140)184.3 ± 117.5(n = 48)194.7 ± 124.0(n = 54)
Serum phosphate (mg/dL)3.8 ± 0.5 (n = 208)3.9 ± 0.6 (n = 127)3.8 ± 0.6 (n = 156)3.8 ± 0.4 (n = 76)3.8 ± 0.6 (n = 53)
25(OH) vitamin D (ng/mL)33.7 ± 12.7 (n = 178)30.7 ± 10.2 (n = 124)34.1 ± 10.5 (n = 142)34.2 ± 10.8 (n = 62)36.6 ± 12.7 (n = 57)
Serum magnesium (mg/dL)2.1 ± 0.2 (n = 139)1.9 ± 0.2(n = 85)1.9 ± 0.2(n = 89)1.9 ± 0.2(n = 53)1.9 ± 0.2(n = 53)
Serum uric acid (mg/dL)4.4 ± 1.0 (n = 73)5.5 ± 1.1(n = 40)5.3 ± 1.2(n = 54)5.2 ± 1.4(n = 36)4.9 ± 1.4(n = 19)

Mean ± SD. Indicates significant differences vs. basal.