Single-Cell RNA Sequencing Analysis of Steroidogenesis and Spermatogenesis Impairment in the Testis of db/db Mice

Figure 4

Differentially expressed genes between db/db and C57BL/6J mice. (a) Hbb-bs, Jun, Akr1b7, Igfbp5, Ctla2a, Ccl7, and Ptgds mRNA expression in the testicular tissue from db/db (n = 3) and C57BL/6J (n = 3) mice was tested using reverse transcription PCR; . (b) Ligand-receptor interactions of Sertoli cells and other cells. The color (log 2 mean) of the circle represents the log of average expression level, and the size of the circle represents the value; a larger point is more reliable. (c) Ligand-receptor interactions of Leydig cells and other cells. (d) The differentially expressed genes in Macrophages and T cells. The size of the circle represents the value.

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