Research Article

Single-Cell RNA Sequencing Analysis of Steroidogenesis and Spermatogenesis Impairment in the Testis of db/db Mice

Table 2

Differentially expressed genes in Leydig cells of db/db mouse.

Gene IDGene nameOfficial full nameAdjusted valuelog2fcPct

16011Igfbp5Insulin-like growth factor binding protein 58.13E − 05−0.539070.908
12834Col6a2Collagen, type VI, alpha 24.81E − 04−0.328790.892
13024Ctla2aCytotoxic T lymphocyte-associated protein 2 alpha0.007219−1.726740.862
11816ApoeApolipoprotein E0.014743−1.708780.554
16149Cd74CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen associated)1.64E − 090.6770031
14960H2-AaHistocompatibility 2, class II antigen A, alpha1.64E − 090.6094211
14969H2-Eb1Histocompatibility 2, class II antigen E beta1.64E − 090.3665591
52033PbkPDZ binding kinase0.0056560.2914961
100039095Gm2044lncRNA0.0056560.380961
8190MiaMIA SH3 domain containing0.0399670.5318161

Log2fc: log2 fold change; Pct: the percentage of cells with this gene.