International Journal of Genomics

Research Article

ATP-Binding Cassette Systems of Brucella

Table 1

Reconstruction and comparative inventories of Brucella ABC systems.


Number	Family	Subfamily	Substrate/Function	Type	B. melitensis	B. abortus	B.suis	B. ovis	B. canis

1	ART	REG	Involved in gene expression regulation	ABC2	BMEI0288	BruAb11738	BR1753	BOV_1692	BCAN_A1791

2	ART	REG	Involved in gene expression regulation	ABC2	BMEI0553	BruAb11451	BR1456	BOV_1411	BCAN_A1491

3	ART	REG	Involved in gene expression regulation	ABC2	BMEI1258	BruAb10711	BR0692	BOV_0683	BCAN_A0704

4	CBY	CBU	Cobalt import	ABC	BMEI0635	BruAb11365	BR1368	BOV_1324	BCAN_A1395
	CBY	CBU	Cobalt import	IM	BMEI0637	BruAb11364	BR1367	BOV_1323	BCAN_A1394, CbiQ

5	CCM		Possibly heme export	IM	BMEI1851		BR0096, ccmC	BOV_0094	BCAN_A0098, ccmC
	CCM		Possibly heme export	IM	BMEI1852		BR0095, ccmB	BOV_0093	BCAN_A0097, ccmB
	CCM		Possibly heme export	ABC	BMEI1853		BR0094, ccmA	BOV_0092	BCAN_A0096, ccmA

6	CDI		Involved in cell division	IM	BMEI0073, ftsX	BruAb11971	BR1996		BCAN_A2042
	CDI		Involved in cell division	ABC	BMEI0072, ftsE	BruAb11972, ftsE	BR1997, ftsE		BCAN_A2043, ftsE

7	CLS		O antigen export system	ABC	BMEI1416, rfbB		BR0519, rfbE	BOV_0523	BCAN_A0531, rfbB
	CLS		O antigen export system	IM	BMEI1415, rfbD		BR0520, rfbD	BOV_0524	BCAN_A0532, rfbD

8	DLM (ABCY)		D-L-Methionine and derivatives import	LPP	BMEI1954

9	DLM (ABCY)		D-L-Methionine and derivatives import	IM	BMEII0336	BruAb20271	BRA0962	BOV_A0903	BCAN_B0983
	DLM (ABCY)		D-L-Methionine and derivatives import	ABC	BMEII0337	BruAb20272	BRA0961	BOV_A0902	BCAN_B0982
	DLM (ABCY)		D-L-Methionine and derivatives import	LPP	BMEII0338	BruAb20273	BRA0960

10	DPL	CYD	Cytochrome bd biogenesis and cysteine export	IM-ABC	BMEII0761, cydC	BruAb20713	BRA0509	BOV_A0443	BCAN_B0508
	DPL	CYD	Cytochrome bd biogenesis and cysteine export	IM-ABC	BMEII0762, cydD	BruAb20714, cydD	BRA0508, cydD	BOV_A0442	BCAN_B0507, CydD

11	DPL	MDL	Involved in mitochondrial export systems	IM-ABC	BMEI0323, msbA	BruAb11700	BR1715	BOV_1657	BCAN_A1753

12	DPL	HMT	Involved in mitochondrial export systems	IM-ABC	BMEI0472	BruAb11533	BR1545	BOV_1493	BCAN_A1581
	DPL	HMT	Involved in mitochondrial export systems	IM-ABC	BMEI0471	BruAb11534	BR1544	BOV_1494	BCAN_A1582

13	DPL	PRT	Proteases, lipase, S-layer protein export	OMP	BMEI1029, TolC	BruAb10954			BCAN_A0957

14	DPL	CHV	Beta-(1–>2) glucan export	IM-ABC	BMEI0984	BruAb11004	BR0998		BCAN_A1015

15	DPL	HMT	Heavy metal tolerance protein	IM-ABC	BMEI1492	BruAb10321	BR0442	BOV_0449	BCAN_A0446

16	DPL	HMT	Involved in mitochondrial export systems	IM-ABC	BMEI1743
	DPL	HMT	Involved in mitochondrial export systems	IM-ABC	BMEI1742			BOV_0198

17	DPL	LIP	Involved in lipid A or polysaccharide export	IM-ABC	BMEII0250	BruAb20990	BRA1050	BOV_A0988	BCAN_B1071

18	DRI	YHIH	Unknown	IM	BMEI0656	BruAb11347	BR1349	BOV_1307	BCAN_A1377
	DRI	YHIH	Unknown	IM	BMEI0655
	DRI	YHIH	Unknown	ABC2	BMEI0654	BruAb11348	BR1350 (ABC2-IM)	BOV_1308	BCAN_A1378
	DRI	YHIH	Unknown	MFP	BMEI0653	BruAb11349	BR1351	BOV_1309	BCAN_A1379

19	DRI	YHIH	Unknown	IM	BMEII0801	BruAb20757	BRA0465		BCAN_B0467
	DRI	YHIH	Unknown	ABC	BMEII0802, drrA	BruAb20758	BRA0464	BOV_A0403	BCAN_B0466
	DRI	YHIH	Unknown	MFP	BMEII0803	BruAb20759	BRA0463	BOV_A0404	BCAN_B0465

20	DRI	NOS	Nitrous oxide reduction	IM	BMEII0970, nosY	BruAb20902, nosY	BRA0278, nosY	BOV_A0254	BCAN_B0280
	DRI	NOS	Nitrous oxide reduction	ABC	BMEII0971, nosF	BruAb20903, nosF	BRA0277, nosF	BOV_A0253	BCAN_B0279
	DRI	NOS	Nitrous oxide reduction	SS	BMEII0972	BruAb20904, nosD	BRA0276, nosD	BOV_A0252	BCAN_B0278

21	FAE		Fatty acid export	IM-ABC	BMEI0520	BruAb11484	BR1490		BCAN_A1528

22	FAE		Fatty acid export	IM-ABC	BMEII0976	BruAb20908		BOV_A0247	BCAN_B0273

23	HAA		Branched-chain amino acids	IM	BMIE0258, LivH	BruAb11771	BR1790	BOV_1725	BCAN_A1829
	HAA		Branched-chain amino acids	IM	BMIE0259, LivM	BruAb11772	BR1791	BOV_1724	BCAN_A1828
	HAA		Branched-chain amino acids	ABC	BMEI0260, braF	BruAb11770	BR1788	BOV_1723	BCAN_A1827
	HAA		Branched-chain amino acids	ABC	BMEI0261, braG	BruAb11769	BR1789	BOV_1722	BCAN_A1826
	HAA		Branched-chain amino acids	BP	BMEI0263	BruAb11765	BR1785	BOV_1720	BCAN_A1823
	HAA		Branched-chain amino acids	BP	BMEI0264	BruAb11767	BR1782		BCAN_A1820
	HAA		Branched-chain amino acids	BP	BMEI0265			BOV_1719

24	HAA		Branched-chain amino acids	BP	BMEI1930		BR0014	BOV_0012	BCAN_A0014

25	HAA		Branched-chain amino acids	ABC	BMEII0065, livF	BruAb20027	BRA0028	BOV_A0025	BCAN_B0030
	HAA		Branched-chain amino acids	ABC	BMEII0066, livG	BruAb20028	BRA0027	BOV_A0024	BCAN_B0029
	HAA		Branched-chain amino acids	IM	BMEII0067, livM	BruAb20025	BRA0026	BOV_A0023	BCAN_B0028
	HAA		Branched-chain amino acids	IM	BMEII0068, livH	BruAb20026	BRA0025	BOV_A0022	BCAN_B0027
	HAA		Branched-chain amino acids	BP	BMEII0069	BruAb20024	BRA0024	BOV_A0021	BCAN_B0026

26	HAA		Branched-chain amino acids	ABC	BMEII0098	BruAb21132	BRA1197	BOV_A1099	BCAN_B1227
	HAA		Branched-chain amino acids	ABC	BMEII0099	BruAb21133	BRA1196	BOV_A1098	BCAN_B1226
	HAA		Branched-chain amino acids	IM	BMEII0101	BruAb21131	BRA1194	BOV_A1097	BCAN_B1225
	HAA		Branched-chain amino acids	IM	BMEII0102	BruAb21130	BRA1195	BOV_A1096	BCAN_B1224
	HAA		Branched-chain amino acids	BP	BMEII0103	BruAb21129	BRA1193	BOV_A0195	BCAN_B1223

27	HAA		Branched-chain amino acids	ABC	BMEII0119	BruAb21111	BRA1176	BOV_A1079	BCAN_B1207
	HAA		Branched-chain amino acids	IM-ABC	BMEII0120	BruAb21112	BRA1175	BOV_A1078	BCAN_B1206
	HAA		Branched-chain amino acids	IM	BMEII0121	BruAb21110	BRA1174		BCAN_B1205
	HAA		Branched-chain amino acids	BP	BMEII0122	BruAb21109	BRA1173	BOV_A1076	BCAN_B1204

28	HAA		Branched-chain amino acids	IM	BMEII0340	BruAb20276	BRA0957		BCAN_B0977
	HAA		Branched-chain amino acids	IM	BMEII0341	BruAb20277	BRA0956	BOV_A0897	BCAN_B0978
	HAA		Branched-chain amino acids	ABC	BMEII0342	BruAb20278	BRA0955	BOV_A0896	BCAN_B0976
	HAA		Branched-chain amino acids	ABC	BMEII0343	BruAb20279	BRA0954	BOV_A0895	BCAN_B0975
	HAA		Branched-chain amino acids	BP	BMEII0344	BruAb20280	BRA0953	BOV_A0894	BCAN_B0974

29	HAA		Branched-chain amino acids	ABC	BMEII0628	BruAb20574	BRA0652	BOV_A0613	BCAN_B0652
	HAA		Branched-chain amino acids	ABC	BMEII0629	BruAb20575	BRA0651	BOV_A0614	BCAN_B0651
	HAA		Branched-chain amino acids	IM	BMEII0630	BruAb20577	BRA0650	BOV_A0611	BCAN_B0649
	HAA		Branched-chain amino acids	IM	BMEII0632	BruAb20576	BRA0649	BOV_A0612	BCAN_B0650
	HAA		Branched-chain amino acids	BP	BMEII0633	BruAb20578	BRA0648	BOV_A0610	BCAN_B0648

30	HAA		Branched-chain amino acids	BP	BMEII0875	BruAb20801	BRA0392		BCAN_B0398
	HAA		Branched-chain amino acids	BP	BMEII0868	BruAb20809	BRA0400	BOV_A0343	BCAN_B0395
	HAA		Branched-chain amino acids	ABC	BMEII0874	BruAb20806	BRA0395	BOV_A0338	BCAN_B0389
	HAA		Branched-chain amino acids	ABC	BMEII0873	BruAb20807	BRA0394	BOV_A0337	BCAN_B0396
	HAA		Branched-chain amino acids	IM		BruAb20808	BRA0393	BOV_A0336	BCAN_B0397

31	ISB (ABCX)		Iron/sulphur centre biogenesis	CYTP	BMEI1040	BruAb10941	BR0931
	ISB (ABCX)		Iron/sulphur centre biogenesis	CYTP	BMEI1042	BruAb10940	BR0933
	ISB (ABCX)		Iron/sulphur centre biogenesis	ABC	BMEI1041	BruAb10942	BR0932

32	ISVH		Iron-siderophores, VB12 and Hemin import	ABC	BMEI0660	BruAb11342	BR1344	BOV_1302	BCAN_A1371
	ISVH		Iron-siderophores, VB12 and Hemin import	IM	BMEI0659	BruAb11343	BR1345	BOV_1304	BCAN_A1372
	ISVH		Iron-siderophores, VB12 and Hemin import	OMR	BMEI0657	BruAb11344	BR1347	BOV_1306	BCAN_A1374
	ISVH		Iron-siderophores, VB12 and Hemin import	BP	BMEI0658	BruAb11345	BR1346	BOV_1305	BCAN_A1373

33	ISVH		Iron(III) dicitrate import	BP	BMEII0535	BruAb20476	BRA0756	BOV_A0705	BCAN_B0763
	ISVH		Iron(III) dicitrate import	IM	BMEII0536, fecD	BruAb20477	BRA0755	BOV_A0704	BCAN_B0764
	ISVH		Iron(III) dicitrate import	ABC	BMEII0537, fecE	BruAb20478	BRA0754	BOV_A0703	BCAN_B0762

34	ISVH		Iron(III) import	ABC	BMEII0604	BruAb20550	BRA0678	BOV_A0635	BCAN_B0677
	ISVH		Iron(III) import	IM	BMEII0605, fatC	BruAb20551	BRA0676	BOV_A0634	BCAN_B0675
	ISVH		Iron(III) import	IM	BMEII0606, fatD	BruAb20552	BRA0677	BOV_A0633	BCAN_B0676
	ISVH		Iron(III) import	BP	BMEII0607	BruAb20553	BRA0675	BOV_A0632	BCAN_B0674

35	MET		Zinc import	IM	BMEII0176, ZnuB	BruAb21061, ZnuB	BRA1124, ZnuB	BOV_A1029	BCAN_B1152
	MET		Zinc import	ABC	BMEII0177, ZnuC	BruAb21060, ZnuC	BRA1123, ZnuC	BOV_A1028	BCAN_B1151
	MET		Zinc import	BP	BMEII0178, ZnuA	BruAb21059, ZnuA	BRA1122, ZnuA	BOV_A1027	BCAN_B1150

36	MKL		Involved in toluene tolerance	ABC	BMEI0964	BruAb11025	BR1020	BOV_0987
	MKL		Involved in toluene tolerance	IM	BMEI0965, ttg2B	BruAb1024	BR1019	BOV_0986
	MKL		Involved in toluene tolerance	SS	BMEI0963, ttg2C	BruAb11026	BR1021	BOV_0988

37	MOI		Thiamine import	ABC	BMEI0283, thiQ	BruAb11744	BR1759	BOV_1698	BCAN_A1798
	MOI		Thiamine import	IM	BMEI0284, thiP	BruAb11743, thiP	BR1758, thiP	BOV_1696	thiP, BCAN_A1797
	MOI		Thiamine import	BP	BMEI0285	BruAb11744, thiB	BR1757, thiB	BOV_1695	thiB, BCAN_A1796
38	MOI		Putrescine import	BP	BMEI0411, potF	BruAb11599	BR1612	BOV_1556	BCAN_A1649
	MOI		Putrescine import	ABC	BMEI0412	BruAb11598	BR1611	BOV_1555	BCAN_A1648
	MOI		Putrescine import	IM	BMEI0413	BruAb11596	BR1609	BOV_1554	BCAN_A1647
	MOI		Putrescine import	IM	BMEI0414	BruAb11597	BR1610	BOV_1553	BCAN_A1646

39	MOI		Sulphate import	IM	BMEI0675, cysW	BruAb11328, cysW2	BR1328, cysW2	BOV_1288	CysW, BCAN_A1353
	MOI		Sulphate import	IM	BMEI0674, cysT	BruAb11329	BR1329	BOV_1289	CysT, BCAN_A1354
	MOI		Sulphate import	BP	BMEI0673	BruAb11330	BR1330	BOV_1290	BCAN_A1355

40	MOI		Sulphate import	ABC	BMEI1838 cysA	BruAb10107	BR0110	BOV_0107	CysA, BCAN_A0113
	MOI		Sulphate import	IM	BMEI1839, cysW	BruAb10106	BR0109, cysW1	BOV_0106	CysW, BCAN_A0112
	MOI		Sulphate import	IM	BMEI1840, cyst	BruAb10105, cysT	BR0108	BOV_0105	CysT, BCAN_A0111
	MOI		Sulphate import	BP	BMEI1841	BruAb10104	BR0107	BOV_0104	BCAN_A0110

41	MOI		Phosphate import	ABC	BMEI1986, pstB	BruAb12116, pstB	BR2141, pstB	BOV_2056	BCAN_A2185, pstB
	MOI		Phosphate import	IM	BMEI1987, pstA	BruAb12114, pstC	BR2139, pstC	BOV_2055	BCAN_A2184, pstA
	MOI		Phosphate import	IM	BMEI1988, pstC	BruAb12115, pstA	BR2140	BOV_2054	BCAN_A2183, pstC
	MOI		Phosphate import	BP	BMEI1989	BruAb12113	BR2138	BOV_2053	BCAN_A2128

42	MOI		Molybdenum import	ABC	BMEII0003, modC	BruAb20090	BRA0090, modC	BOV_A0084	BCAN_B0093, ModC
	MOI		Molybdenum import	IM	BMEII004, modB	BruAb20089	BRA0089, modB	BOV_A0083	BCAN_B0092, ModB
	MOI		Molybdenum import	BP	BMEII0005	BruAb20088	BRA0088, modA	BOV_A0082	BCAN_B0091

43	MOI		Spermidine/putrescine import	ABC	BMEII0193, potA	BruAb21046	BRA1107		BCAN_B1129
	MOI		Spermidine/putrescine import	IM	BMEII0194, potB	BruAb21044	BRA1106		BCAN_B1128
	MOI		Spermidine/putrescine import	IM	BMEII0195, potC	BruAb21045	BRA1105		BCAN_B1127
	MOI		Spermidine/putrescine import	BP	BMEII0196	BruAb21043	BRA1104		BCAN_B1126

44	MOI		Unknown	BP	BMEII0479	BruAb20422	BRA0810	BOV_A0760	BCAN_B0824
	MOI		Unknown	ABC	BMEII0481	BruAb20423	BRA0809	BOV_A0759	BCAN_B0823
	MOI		Unknown	IM	BMEII0483	BruAb20424	BRA0807	BOV_A0758	BCAN_B0822
	MOI		Unknown	IM	BMEII0484	BruAb20425	BRA0808	BOV_A0757	BCAN_B0821

45	MOI		Iron(III) import	BP	BMEII0565	BruAb20510	BRA0720	BOV_A0676	BCAN_B0726
	MOI		Iron(III) import	IM2	BMEII0566	BruAb20511	BRA0719	BOV_A0675	BCAN_B0274
	MOI		Iron(III) import	ABC	BMEII0567	BruAb20512	BRA0718	BOV_A0674	BCAN_B0725

46	MOI		Iron(III) import	ABC	BMEII0583	BruAb20529	BRA0701	BOV_A0656	BCAN_B0702
	MOI		Iron(III) import	BP	BMEII0584	BruAb20530	BRA0700	BOV_A0655	BCAN_B0703
	MOI		Iron(III) import	IM2	BMEII0585	BruAb20531	BRA0699	BOV_A0654	BCAN_B0701

47	MOI		Spermidine/putrescine import	IM	BMEII0920, potC	BruAb20852	BRA0328	BOV_A0303	BCAN_B0331
	MOI		Spermidine/putrescine import	IM	BMEII0921, potB	BruAb20853	BRA0329	BOV_A0302	BCAN_B0330
	MOI		Spermidine/putrescine import	ABC	BMEII0922, potA	BruAb20855	BRA0327	BOV_A0301	BCAN_B0329
	MOI		Spermidine/putrescine import	BP	BMEII0923, potD	BruAb20854	BRA0326	BOV_A0300	BCAN_B0328

48	MOI		Iron(III) import	BP	BMEII1120	BruAb20113	BRA0115	BOV_A0105	BCAN_B0119
	MOI		Iron(III) import	IM	BMEII1121, sufB	BruAb20111	BRA0114	BOV_A0104	BCAN_B0118
	MOI		Iron(III) import	IM	BMEII1122, sufB	BruAb20112	BRA0113	BOV_A0103	BCAN_B0117
	MOI		Iron(III) import	ABC	BMEII1123, sufC	BruAb20110	BRA0112	BOV_A0102	BCAN_B0116

49	New1		Unknown	IM	BMEI0013	BruAb12030	BR2055	BOV_1975	BCAN_A2101
	New1		Unknown	ABC	BMEI0012	BruAb12031	BR2056		BCAN_A2102
	New1		Unknown	BP	BMEI0014
	New1		Unknown	BP	BMEI0015

50	MOS		Ribose import	ABC2	BMEI0391	BruAB11620, rbsA-2	BR1632, rbsA-2	BOV_1576	BCAN_A1669
	MOS		Ribose import	IM	BMEI0392	BruAB11619, rbsC-2	BR1631, rbsC-2	BOV_1575, rbsC2	BCAN_A1668
	MOS		Ribose import	BP	BMEI0393	BruAB11618	BR1630	BOV_1574	BCAN_A1667

51	MOS		Ribose Import	ABC	BMEI0665	BruAb11337	BR1339	BOV_1299	BCAN_A1367
	MOS		Ribose Import	IM	BMEI0664	BruAb11338	BR1340	BOV_1300	BCAN_A1368
	MOS		Ribose Import	BP	BMEI0663	BruAb11340	BR1342	BOV_1301	BCAN_A1369
	MOS		Ribose Import	BP	BMEI0662	BruAb11335

52	MOS		Ribose import	BP	BMEI1390	BruAb10566, rbsB1	BR0544, rbsB1	BOV_0546 rbsB1	BCAN_A0557
	MOS		Ribose import	IM	BMEI1391, rbsC	BruAb10565, rbsC1	BR0543, rbsC1	BOV_0545 rbsC1	BCAN_A0555
	MOS		Ribose import	ABC2	BMEI1392, rbsA	BruAb10564, rbsA1	BR0542, rbsA1	BOV_0544 rbsA1	BCAN_A0554, rsbA

53	MOS		Possibly galactoside	BP	BMEII0083	BruAb20010	BRA0010	BOV_A0007
	MOS		Possibly galactoside	ABC2	BMEII0085, mglA	BruAb20009	BRA0009	BOV_A0006
	MOS		Possibly galactoside	IM	BMEII0086, mglC	BruAb20007	BRA0007	BOV_A0005
	MOS		Possibly galactoside	IM	BMEII0087	BruAb20008	BRA0008	BOV_A0004

54	MOS		Xylose import	IM	BMEII0144, xylH	BruAb21089, xylH	BRA1152, xylH	BOV_A1057	BCAN_B1181
	MOS		Xylose import	ABC2	BMEII0145, xylG	BruAb21088, xylG	BRA1151, xylG	BOV_A1056	BCAN_B1180, xylG
	MOS		Xylose import	BP	BMEII0146, xylF	BruAb21087, xylF	BRA1150, xylF	BOV_A1055	BCAN_B1179, xylF

55	MOS		Ribose import	ABC2	BMEII0300, rbsA	BruAb20239rbsA4	BRA0995, rbsA4	BOV_A0937	BCAN_B1014
	MOS		Ribose import	IM	BMEII0301 rbsC	BruAb20240,rbsC5	BRA0993, rbsC5		BCAN_B1013
	MOS		Ribose import	IM	BMEII0302 rbsC	BruAb20239, rbsC4	BRA0994, rbsC5	BOV_A0935	BCAN_B1012
	MOS		Ribose import	BP		BruAb20238	BRA0996, rbsB3	BOV_A0938	BCAN_B1015

56	MOS		Monosaccharide import	BP	BMEII0360, chvE	BruAb20296	BRA0937	BOV_A0879	BCAN_B0957
	MOS		Monosaccharide import	ABC2	BMEII0361	BruAb20297	BRA0936	BOV_A0878	BCAN_B0956
	MOS		Monosaccharide import	IM	BMEII0362	BruAb20298	BRA0935	BOV_A0877	BCAN_B0955

57	MOS		Erythritol import	ABC2	BMEII0432, rbsA	BruAb20371, rbsA3	BRA0860, rbsA3	BOV_A0807, rsbA3	BCAN_B0877
	MOS		Erythritol import	IM	BMEII0433, rbsC	BruAb20372, rbsC3	BRA0859, rbsC3		BCAN_B0876
	MOS		Erythritol import	BP	BMEII0435	BruAb20373, rbsB2	BRA0858, rbsB2	BOV_A0805	BCAN_B0875

58	MOS		Galactoside/Ribose import	ABC2	BMEII0698	BruAb20654	BRA0570	BOV_A0533	BCAN_B0570
	MOS		Galactoside/Ribose import	IM				BOV_A0534	BCAN_B0567
	MOS		Galactoside/Ribose import	IM	BMEII0700	BruAb20655	BRA0568	BOV_A0535
	MOS		Galactoside/Ribose import	IM	BMEII0701	BruAb20656	BRA0569		BCAN_B0568
	MOS		Galactoside/Ribose import	BP	BMEII0702		BRA0567	BOV_A0532	BCAN_B0567

59	MOS		Monosaccharide import	IM	BMEII0981	BruAb20913	BRA0267	BOV_A0242	BCAN_B0268
	MOS		Monosaccharide import	ABC2	BMEII0982	BruAb20914	BRA0266	BOV_A0241	BCAN_B0267
	MOS		Monosaccharide import	BP	BMEII0983	BruAb20916	BRA0265	BOV_A0240	BCAN_B0266

60	o228		Unknown	IM	BMEI0361
	O228		Unknown	MFP	BMEI0359
	o228		Unknown	ABC	BMEI0360

61	o228		Unknown	IM		BruAb10085	BR0087	BOV_0085
	O228		Unknown	MFP					BCAN_A1712
	o228		Unknown	ABC		BruAb10084	BR0086	BOV_0084	BCAN_A1711

62	o228		Unknown	MFP		BruA11658	BR1671	BOV_1617
	o228		Unknown	IM-ABC		BruA11657	BR1670	BOV_1616	BCAN_A0087

63	o228		Lipoprotein release system	ABC	BMEI1138, LolD	BruAb10838,LolD	BR0824, LolD	BOV_0818	BCAN_A0839
	o228		Lipoprotein release system	IM	BMEI1139, LolE	BruAb10837, LolE	BR0823, LolE	BOV_0817	BCAN_A0838

64	OPN		Dipeptide import	ABC	BMEI0438, dppF	BruAb11569	BR1582	BOV_1527	BCAN_A1617
	OPN		Dipeptide import	ABC	BMEI0437, dppD	BruAb11570	BR1583	BOV_1528	BCAN_A1618
	OPN		Dipeptide import	IM	BMEI0435, dppC	BruAb11571	BR1584	BOV_1530	BCAN_A1620
	OPN		Dipeptide import	IM	BMEI0436, dppC	BruAb11572	BR1585	BOV_1529	BCAN_A1619
	OPN		Dipeptide import	BP	BMEI0433, dppA	BruAb11573	BR1586	BOV_1531	BCAN_A1621

65	OPN		Oligopeptide import	ABC2	BMEI1938, oppD	BruAb10006	BR0006	BOV_0006	BCAN_A0006
	OPN		Oligopeptide import	BP	BMEI1934	BruAb10007	BR0007	BOV_0009	BCAN_A0010
	OPN		Oligopeptide import	BP	BMEI1935	BruAb10008	BR0008	BOV_0010	BCAN_A0009
	OPN		Oligopeptide import	IM	BMEI1936, oppB	BruAb10009	BR0009	BOV_0008	BCAN_A0008
	OPN		Oligopeptide import	IM	BMEI1937, oppC	BruAb10010	BR0010	BOV_0007	BCAN_A0007

66	OPN		Oligopeptide import	ABC	BMEII0199, oppF	BruAb21039	BRA1100
	OPN		Oligopeptide import	ABC	BMEII0200, oppD	BruAb21040	BRA1101		BCAN_B1123
	OPN		Oligopeptide import	IM	BMEII0201, oppC	BruAb21037	BRA0099		BCAN_B1122
	OPN		Oligopeptide import	IM	BMEII0202, oppB	BruAb21038	BRA0098		BCAN_B1121
	OPN		Oligopeptide import	BP	BMEII01203	BruAb21036	BRA0097		BCAN_B1119

67	OPN		Dipeptide import	ABC	BMEII0205, dppF	BruAb21033	BRA1095	BOV_A0950	BCAN_B1117
	OPN		Dipeptide import	ABC	BMEII0206, dppD	BruAb21034	BRA1094	BOV_A0951	BCAN_B1116
	OPN		Dipeptide import	IM	BMEII0207, dppC	BruAb21031	BRA1093		BCAN_B1115, dppC
	OPN		Dipeptide import	IM		BruAb21032	BRA1092	BOV_A0952
	OPN		Dipeptide import	IM	BMEII0209, dppB			BOV_A0953	BCAN_B1114
	OPN		Dipeptide import	BP	BMEII0210	BruAb21030	BRA1090	BOV_A0954	BCAN_B1113

68	OPN		Dipeptide/ Oligopeptide import	BP	BMEII0217	BruAb21024	BRA1084		BCAN_B1107
	OPN		Dipeptide/ Oligopeptide import	IM	BMEII0220	BruAb21020	BRA1081		BCAN_B1104
	OPN		Dipeptide/ Oligopeptide import	IM	BMEII0221	BruAb21021	BRA1080		BCAN_B1103
	OPN		Dipeptide/ Oligopeptide import	ABC	BMEII0222	BruAb21018	BRA1079		BCAN_B1102
	OPN		Dipeptide/ Oligopeptide import	ABC	BMEII0223	BruAb21019	BRA1078		BCAN_B1101

69	OPN		Dipeptide import	BP	BMEII0284	BruAb20952	BRA1012	BOV_A0504	BCAN_B1032
	OPN		Dipeptide import	IM	BMEII0285	BruAb20950	BRA1009	BOV_A0501	BCAN_B1031
	OPN		Dipeptide import	IM	BMEII0286	BruAb20951	BRA1008	BOV_A0502	BCAN_B1030
	OPN		Dipeptide import	ABC	BMEII0287	BruAb20948	BRA1011	BOV_A0500	BCAN_B1029
	OPN		Dipeptide import	ABC	BMEII0288	BruAb20949	BRA1010	BOV_A0501	BCAN_B1028

70	OPN		Nickel import	BP	BMEII0487	BruAb20428	BRA0804	BOV_A0754	BCAN_B0818, NikA
	OPN		Nickel import	IM	BMEII0488, nikB	BruAb20429, nikB	BRA0802, nikC	BOV_A0752	BCAN_B0817, NikB
	OPN		Nickel import	IM	BMEII0489, nikC	BruAb20430, nikV	BRA0803, nikB	BOV_A0753	BCAN_B0816, NikC
	OPN		Nickel import	ABC	BMEII0490, nikD	BruAb20431, nikD	BRA0800, nikE	BOV_A0751	BCAN_B0815, NikD
	OPN		Nickel import	ABC	BMEII0491, nikE	BruAb20432, nikE	BRA0801, nikD		BCAN_B0814, NikE

71	OPN		Oligopeptide import	BP	BMEII0504	BruAb20446	BRA0783	BOV_A0737	BCAN_B0800
	OPN		Oligopeptide import	IM	BMEII0505	BruAb20447	BRA0788	BOV_A0736	BCAN_B0799
	OPN		Oligopeptide import	IM	BMEII0506	BruAb20448	BRA0787	BOV_A0735	BCAN_B0798
	OPN		Oligopeptide import	ABC	BMEII0507	BruAb20449	BRA0786	BOV_A0734	BCAN_B0797
	OPN		Oligopeptide import	ABC	BMEII0508			BOV_A0733	BCAN_B0796

72	OPN		Oligopeptide import	BP	BMEII0691	BruAb20648	BRA0576	BOV_A0542

73	OPN		Oligopeptide import	BP	BMEII0734	BruAb20684	BRA0538	BOV_A0468	BCAN_B0538
	OPN		Oligopeptide import	BP	BMEII0735, oppA	BruAb20685	BRA0537	BOV_A0467	BCAN_B0537
	OPN		Oligopeptide import	IM	BMEII0736	BruAb20686	BRA0536	BOV_A0466	BCAN_B0535
	OPN		Oligopeptide import	IM	BMEII0737	BruAb20687	BRA0535	BOV_A0465	BCAN_B0536
	OPN		Oligopeptide import	ABC2	BMEII0738	BruAb20688	BRA0534	BOV_A0464	BCAN_B0534

74	OPN		Oligopeptide import	BP	BMEII0859	BruAb20792	BRA0409	BOV_A0352	BCAN_B0412
	OPN		Oligopeptide import	IM	BMEII0860		BRA0408	BOV_A0351	BCAN_B0411
	OPN		Oligopeptide import	IM	BMEII0861	BruAb20794	BRA0407	BOV_A0350	BCAN_B0410
	OPN		Oligopeptide import	ABC	BMEII0863	BruAb20796	BRA0405	BOV_A0347	BCAN_B0408
	OPN		Oligopeptide import	ABC	BMEII0864	BruAb20797	BRA0404	BOV_A0348	BCAN_B0407

75	OSP		Maltose import	ABC	BMEI1713, malK	BruAb10233	BR0238	BOV_0231	BCAN_A0241
	OSP		Maltose import	IM	BMEI1714, malG	BruAb10231	BR0237	BOV_0230	BCAN_A0240
	OSP		Maltose import	IM	BMEI1715, malF	BruAb10232	BR0236	BOV_0229	BCAN_A0239
	OSP		Maltose import	BP	BMEI1716	BruAb10230	BR0235	BOV_0228	BCAN_A0238

76	OSP		Oligosaccharide or polyol import	ABC	BMEII0112, ugpC	BruAb21119	BRA1183	BOV_A1086	BCAN_B1214
	OSP		Oligosaccharide or polyol import	IM	BMEII0113, ugpA	BruAb21118	BRA1181	BOV_A1085	BCAN_B1213
	OSP		Oligosaccharide or polyol import	IM	BMEII0114, ugpE	BruAb21117	BRA1182	BOV_A1084	BCAN_B1212
	OSP		Oligosaccharide or polyol import	BP	BMEII0115	BruAb21116	BRA1180		BCAN_B1211
77	OSP		Oligosaccharide or polyol import	IM	BMEII0541	BruAb20483	BRA0749	BOV_A0700	BCAN_B0757
	OSP		Oligosaccharide or polyol import	IM		BruAb20482	BRA0750	BOV_A0699	BCAN_B0756
	OSP		Oligosaccharide or polyol import	BP	BMEII0542	BruAb20484	BRA0748	BOV_A0698	BCAN_B0755
	OSP		Oligosaccharide or polyol import	ABC	BMEII0544	BruAb20487	BRA0745	BOV_A0696	BCAN_B0753

78	OSP		Oligosaccharide or polyol import	BP	BMEII0590	BruAb20537	BRA0693	BOV_A0648	BCAN_B0691
	OSP		Oligosaccharide or polyol import	IM	BMEII0591	BruAb20538	BRA0691	BOV_A0647	BCAN_B0690
	OSP		Oligosaccharide or polyol import	IM	BMEII0592	BruAb20539	BRA0692	BOV_A0646	BCAN_B0689
	OSP		Oligosaccharide or polyol import	ABC	BMEII0593	BruAb20540	BRA0690	BOV_A0645	BCAN_B0688

79	OSP		SN-glycerol-3-phosphate import	ABC	BMEII0621, ugpC	BruAb20568, ugpC	BRA0658, ugpC	BOV_A0620	BCAN_B0658
	OSP		SN-glycerol-3-phosphate import	IM	BMEII0622, ugpE	BruAb20569, ugpE	BRA0657, ugpE	BOV_A0619	BCAN_B0657
	OSP		SN-glycerol-3-phosphate import	IM	BMEII0623, ugpE	BruAb20570, ugpA	BRA0656, ugpA	BOV_A0618	BCAN_B0656
	OSP		SN-glycerol-3-phosphate import	IM	BMEII0624, ugpA
	OSP		SN-glycerol-3-phosphate import	BP	BMEII0625	BruAb20571, ugpB	BRA0655, ugpA	BOV_A0617	BCAN_B0655

80	OSP		Oligosaccharide or polyol import	ABC	BMEII0750	BruAb20702	BRA0521	BOV_A0454	BCAN_B0520
	OSP		Oligosaccharide or polyol import	IM	BMEII0752	BruAb20704	BRA0519	BOV_A0452	BCAN_B0518
	OSP		Oligosaccharide or polyol import	IM	BMEII0753	BruAb20705	BRA0518	BOV_A0451	BCAN_B0517
	OSP		Oligosaccharide or polyol import	BP	BMEII0754	BruAb20706	BRA0516	BOV_A0449	BCAN_B0516
	OSP		Oligosaccharide or polyol import	BP	BMEII0755

81	OSP		Maltose import	ABC	BMEII0940	BruAb20874	BRA0307	BOV_A0282	BCAN_B0308
	OSP		Maltose import	IM	BMEII0942	BruAb20875	BRA0306	BOV_A0281	BCAN_B0307
	OSP		Maltose import	IM	BMEII0943	BruAb20876	BRA0305	BOV_A0280	BCAN_B0306
	OSP		Maltose import	BP	BMEII0944			BOV_A0279
	OSP		Maltose import	BP	BMEII0945	BruAb20877	BRA0304		BCAN_B0305

82	OTCN		Glycine betaine/L-proline import	ABC	BMEI0439, proV	BruAb11568	BR1581	BOV_1526	BCAN_A1616
	OTCN		Glycine betaine/L-proline import	IM	BMEI0440, proW	BruAb11567	BR1580	BOV_1525	BCAN_A1615
	OTCN		Glycine betaine/L-proline import	BP	BMEI0441, proX	BruAb11566	BR1579	BOV_1524	BCAN_A1614

83	OTCN		Choline S^S-dependent regulation of yehZYXW	BP	BMEI1725	BruAb10220	BR0225	BOV_0216	BCAN_A0228
	OTCN		Choline S^S-dependent regulation of yehZYXW	IM	BMEI1726, proW	BruAb10217	BR1222	BOV_0215	BCAN_A0227
	OTCN		Choline S^S-dependent regulation of yehZYXW	IM	BMEI1728, proW	BruAb10219	BR0224	BOV_0213	BCAN_A0225
	OTCN		Choline S^S-dependent regulation of yehZYXW	ABC	BMEI1727, proV	BruAb10218	BR0223	BOV_0214	BCAN_A0226

84	OTCN		Osmoprotectants, Taurine, Cyanante & Nitrate	BP	BMEI1737	BruAb10207	BR0211	BOV_0204	BCAN_A0215
	OTCN		Osmoprotectants, Taurine, Cyanante & Nitrate	IM	BMEI1739	BruAb10206	BR0213	BOV_0202	BCAN_A0213
	OTCN		Osmoprotectants, Taurine, Cyanante & Nitrate	ABC		BruAb10208

85	OTCN		Taurine import	BP	BMEII0109	BruAb21122	BRA1186	BOV_A1089	BCAN_B1218
	OTCN		Taurine import	IM	BMEII0107, tauC	BruAb21124	BRA1188	BOV_A1091	BCAN_B1219
	OTCN		Taurine import	ABC	BMEII0108, tauB	BruAb21123	BRA1187	BOV_A1090	BCAN_B1217

86	OTCN		Glycine betaine/L-proline import	ABC	BMEII0548	BruAb20492	BRA0740	BOV_A0692	BCAN_B0748
	OTCN		Glycine betaine/L-proline import	IM	BMEII0549	BruAb20493	BRA0739	BOV_A0691	BCAN_B0747
	OTCN		Glycine betaine/L-proline import	BP	BMEII0550	BruAb20494	BRA0738	BOV_A0690	BCAN_B0746

87	OTCN		Nitrate import	BP	BMEII0797	BruAb20753	BRA0469	BOV_A0406	BCAN_B0471
	OTCN		Nitrate import	ABC	BMEII0798, nrtC	BruAb20755	BRA0467	BOV_A0407	BCAN_B0470
	OTCN		Nitrate import	IM	BMEII0799, nrtB	BruAb20755	BRA0468	BOV_A0408	BCAN_B0469

88	OTCN		Taurine import	ABC	BMEII0961	BruAb10894	BRA0286	BOV_A0262	BCAN_B0288
	OTCN		Taurine import	IM	BMEII0962	BruAb10895	BRA0285	BOV_A0261	BCAN_B0287
	OTCN		Taurine import	BP	BMEII0963	BruAb10896	BRA0284	BOV_A0260	BCAN_B0286

89	PAO		Polar amino acid import	ABC	BMEI0108	BruAb11932	BR1959	BOV_A0336	BCAN_A2004
	PAO		Polar amino acid import	ABC	BMEI0111	BruAb11935	BR1956	BOV_1885	BCAN_A2001
	PAO		Polar amino acid import	IM	BMEI0112	BruAb11931	BR1955	BOV_1882	BCAN_A2000
	PAO		Polar amino acid import	IM	BMEI0113	BruAb11930	BR1954	BOV_1081	BCAN_A1999
	PAO		Polar amino acid import	BP	BMEI0114	BruAb11929	BR1953	BOV_1880	BCAN_A1998
	PAO		Polar amino acid import	BP				BOV_1879

90	PAO		Arginine/Ornithine biding protein precursor	BP		BruAb20594		BOV_A0594
	PAO		Arginine/Ornithine biding protein precursor	BP	BMEI1022	BruAb20595	BRA0632	BOV_A0593
	PAO		Arginine/Ornithine biding protein precursor	BP		BruAb10874	BRA0631	BOV_0945	BCAN_A0967

91	PAO		General L-amino acid import	ABC	BMEI1208, appP	BruAb10762	BR0745	BOV_A0890	BCAN_A0760
	PAO		General L-amino acid import	IM	BMEI1209, appM	BruAb10758	BR0744	BOV_0739	BCAN_A0759
	PAO		General L-amino acid import	IM	BMEI1210, appQ	BruAb10760	BR0743	BOV_0737	BCAN_A0758
	PAO		General L-amino acid import	BP	BMEI1211, appJ	BruAb10761	BR0741	BOV_0738	BCAN_A0756
	PAO		General L-amino acid import	BP	BMEII0349, appJ	BruAb20285	BRA0948	BOV_0736	BCAN_B0969

92	PAO		Arginine	BP	BMEI1627	BruAb10321	BR0295	BOV_0308

93	PAO		Cystine import	ABC	BMEII0599	BruAb20545	BRA0684	BOV_A0640	BCAN_B0682
	PAO		Cystine import	IM	BMEII0600	BruAb20546	BRA0683	BOV_A0639	BCAN_B0681
	PAO		Cystine import	BP	BMEII0601	BruAb20547, fliY	BRA0682, fliY	BOV_A0638, fliY	BCAN_B0680

94	PAO		Polar amino acid import	IM			BR0952		BCAN_A0964
	PAO		Polar amino acid import	IM			BR0953		BCAN_A0965
	PAO		Polar amino acid import	BP	BMEI1104		BR0955	BOV_0854

95	PAO		Polar amino acid import	BP			BR0862	BOV_A0903

96	UVR		DNA repair	ABC2	BMEI0878	BruAb1110, UvrA	UvrA	BOV_1063	BCAN_A1124
97	YHBG		Possible LPS transport to outer membrane	ABC	BMEI1790	BruAb10153	BR157	BOV_0152	BCAN_A0162
	YHBG		Possible LPS transport to outer membrane	SS	BMEI1791	BruAb10152	BR156	BOV_0151	BCAN_A0161

ABC: ATP-Binding Cassette; IM: Inner membrane protein; BP: Binding protein; IM-ABC: Inner membrane protein-ATP binding cassette fusion; ABC2: 2 ABC proteins fused together; OMP: Outer membrane protein; MFP: Membrane fusion protein; SS: Signal sequence; LPP: Extracytoplasmic protein with a lipoprotein type signal sequence; BM: Brucella melitensis; BA: Brucella abortus; BS: Brucella suis; Bold Text: Indicates a frame shift mutation or premature stop codon in these genes.