The Influence of 3′UTRs on MicroRNA Function Inferred from Human SNP Data

<table>Comparison of CVs between different gene groups.  Genes with both miRNA target sites and SNPs have significant larger CVs (one-side Wilcoxon rank sum test, <svg height="14.3625" id="M24" style="vertical-align:-0.30096pt" version="1.1" viewbox="0 0 58.012501 14.3625" width="58.012501" xmlns="http://www.w3.org/2000/svg">
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</svg>).  Gene groups include non-miR no SNP: non-miRNA target genes without SNPs on their 3′UTRs; non-miRNA SNP: non-miRNA target genes with SNPs on their 3′UTRs; miR no SNP: miRNA target genes without SNPs on their 3′UTRs; miR SNP: miRNA target genes with SNPs on their 3′UTRs; seed nt SNP: miRNA target genes with SNPs in the seed target region; excluding seed nt: miRNA target genes with SNPs in the rest but seed target region; 67 nts SNP: miRNA target genes with SNPs in the SNP density window region defined in this study; excluding 67 nts: miRNA target genes with SNPs in the rest but defined density window region.</table>

International Journal of Genomics

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Figure 5

Figure 5: The Influence of 3′UTRs on MicroRNA Function Inferred from Human SNP Data 