Interactome of Radiation-Induced microRNA-Predicted Target Genes

Table 3

Biological pathways controlled by IR-modulated miRNAs and their association with ionizing radiation response.

Identified pathways	Number of miRNA target genes	Association with IR response	Reference
Adherens junction	10	Yes	[42]
Aldosterone-regulated sodium reabsorption	7	Unknown	N/A
Apoptosis	9	Yes	[38]
Cell cycle	12	Yes	[41]
Endocytosis	20	Yes	[35]
Focal adhesion	17	Yes	[43]
Insulin signaling	19	Yes	[37]
Long-term potentiation	11	Unknown	N/A
MAPK signaling	22	Yes	[33]
Neutrotrophin signaling	12	Unknown	N/A
Oocyte meiosis	13	Yes	[44]
p53 signaling	8	Yes	[39]
Regulation of actin cytoskeleton	20	Yes	[34]
Renal cell carcinoma	9	Yes	[45]
TGF-β signaling	10	Yes	[40]
Thyroid cancer	6	Yes	[46]
Ubiquitin-mediated proteolysis	17	Yes	[47]