De Novo Assembly and Comparative Transcriptome Analysis Provide Insight into Lysine Biosynthesis in Toona sinensis Roem

Figure 3

The mechanisms for lysine synthesis. The pathways labeled in the diagram include three variants that use either succinyl-CoA or acetyl-CoA. The first pathways were the acyl-DAP pathways. Another uses Ddh (DAP dehydrogenase) to directly convert THDPA to m-DAP. LL-DAP-AT directly converts THDPA to LL-DAP. Acronyms in the diagram include LsyC, aspartate kinase; Asd, aspartate-semialdehyde dehydrogenase; DapA, dihydrodipicolinate synthase; DapB, dihydrodipicolinate reductase; THDPA, L-2,3,4,5-tetrahydrodipicolinate; DapD, THDPA acyltransferase; DapC, N-acyl-L-2-amino-6-oxopimelate aminotransferase; DapE, N-acyl-LL-2,6-diaminopimelate deacylase; LL-DAP, LL-2,5-diaminopimelate; DapF, DAP epimerase; m-DAP, m-2,6-diaminopimelate; LysA, m-DAP decarboxylase; LL-DAP-AT, LL-diaminopimelate aminotransferase; Ddh, m-DAP dehydrogenase. The red words represent upregulated DEGs; the black words represent not DEGs.