Research Article
Differential MicroRNA Analyses of Burkholderia pseudomallei- and Francisella tularensis-Exposed hPBMCs Reveal Potential Biomarkers
Table 4
GO terms found in the miRNAs differentially expressed in different organism-exposed samples.
| GO term | E. coli-exposed hPBMCs | B. pseudomallei-exposed hPBMCs | F. tularensis-exposed hPBMCs |
| (a) Downregulated miRNAs | Top 1 | Regulation of transcription related | Regulation of transcription related | N/A | Top2 | Protein catabolic process related | Adhesion related | Top 3 | Transcription related | Regulation of RNA metabolic process | Top 4 | Macromolecule catabolic process related | Transcription related | Top 5 | Adhesion related | Intracellular signaling cascade | (b) Upregulated miRNAs | Top 1 | Regulation of transcription related | Regulation of transcription related | Programmed cell death related | Top2 | Transcription related | Transcription related | Regulation of transcription related | Top 3 | Regulation of RNA metabolic process | Regulation of RNA metabolic process | Protein catabolic process related | Top 4 | Programmed cell death related | Cell morphogenesis related | Macromolecule catabolic process related | Top 5 | Macromolecule biosynthetic process regulation | Cell projection related | Ion transport | Top 6 | ā | Programmed cell death related | ā |
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