Research Article

Differential MicroRNA Analyses of Burkholderia pseudomallei- and Francisella tularensis-Exposed hPBMCs Reveal Potential Biomarkers

Table 4

GO terms found in the miRNAs differentially expressed in different organism-exposed samples.

GO termE. coli-exposed hPBMCsB. pseudomallei-exposed hPBMCsF. tularensis-exposed hPBMCs

(a) Downregulated miRNAs
Top 1Regulation of transcription relatedRegulation of transcription relatedN/A
Top2Protein catabolic process relatedAdhesion related
Top 3Transcription relatedRegulation of RNA metabolic process
Top 4Macromolecule catabolic process relatedTranscription related
Top 5Adhesion relatedIntracellular signaling cascade
(b) Upregulated miRNAs
Top 1Regulation of transcription relatedRegulation of transcription relatedProgrammed cell death related
Top2Transcription relatedTranscription relatedRegulation of transcription related
Top 3Regulation of RNA metabolic processRegulation of RNA metabolic processProtein catabolic process related
Top 4Programmed cell death relatedCell morphogenesis relatedMacromolecule catabolic process related
Top 5Macromolecule biosynthetic process regulationCell projection relatedIon transport
Top 6 Programmed cell death related