Identification of Key Genes and Prognostic Value Analysis in Hepatocellular Carcinoma by Integrated Bioinformatics Analysis

Figure 4

Expression and prognostic value of CCNB1 in HCC. (a–d) The expression data collected from 3 datasets from ONCOMINE indicated that CCNB1 expression was upregulated in HCC tissues compared with the normal controls (all ). (e) Expression of CCNB1 was increased in HCC cells based on the data from CCLE. (f) The Kaplan-Meier survival curves revealed that the high CCNB1 expression predicted worse overall survival compared with the low CCNB1 expression in HCC patients (log-rank ). (g) High CCNB1 expression predicted worse overall survival compared with the low CCNB1 expression in HCC patients at tumor stage 1 (log-rank ). (h) High CCNB1 expression predicted worse overall survival compared with the low CCNB1 expression in HCC patients at tumor stage 2 (log-rank ). (i) High CCNB1 expression predicted worse overall survival compared with the low CCNB1 expression in HCC patients at tumor stage 3 (log-rank ).

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