Identification of Key Genes and Prognostic Value Analysis in Hepatocellular Carcinoma by Integrated Bioinformatics Analysis

Figure 5

Expression and prognostic value of CCNB2 in HCC. (a–d) The expression data collected from 3 datasets from ONCOMINE indicated that CCNB2 expression was upregulated in HCC tissues compared with the normal controls (all ). (e) Expression of CCNB2 was increased in HCC cells based on the data from CCLE. (f) The Kaplan-Meier survival curves revealed that the high CCNB2 expression predicted worse overall survival compared with the low CCNB2 expression in HCC patients (log-rank ). (g) No significantly different survival times were observed between patients with high CDK1 expression and patients with low CDK1 expression at tumor stage 1 (log-rank ). (h) High CCNB2 expression predicted worse overall survival compared with the low CCNB2 expression in HCC patients at tumor stage 2 (log-rank ). (i) High CCNB2 expression predicted worse overall survival compared with the low CCNB2 expression in HCC patients at tumor stage 3 (log-rank ).

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