Research Article
Mining the Prognostic Value of HNRNPAB and Its Function in Breast Carcinoma
Table 2
The associations between HNRNPAB mRNA expression and clinicopathological parameters in BC.
| | Variable | Case | mRNA expression | value |
| | Age (years) | | | 0.0029 | | ≤51 | 1099 | ↑ | | | >51 | 3209 | — | | | Nodal status | | | <0.0001 | | Positive | 1646 | ↑ | | | Negative | 2416 | — | | | ER (IHC) | | | <0.0001 | | Positive | 3911 | — | | | Negative | 552 | ↑ | | | PR (IHC) | | | <0.0001 | | Positive | 3498 | — | | | Negative | 829 | ↑ | | | HER2 (IHC) | | | <0.0001 | | Positive | 661 | ↑ | | | Negative | 3582 | — | | | Triple-negative status | | | <0.0001 | | Not TNBC | 4119 | — | | | TNBC | 317 | ↑ | | | Basal-like status | | | <0.0001 | | Not basal-like | 3837 | — | | | Basal-like | 832 | ↑ | | | SBR grade | | | <0.0001 | | SBR1 | 544 | — | | | SBR2 | 1699 | ↑ | | | SBR3 | 1374 | ↑ | | | NPI grade | | | <0.0001 | | NPI1 | 1173 | — | | | NPI2 | 1525 | ↑ | | | NPI3 | 416 | ↑ | |
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Note: ER: estrogen receptor; PR: progesterone receptor; HER2: human epidermal growth factor receptor 2; IHC: immunochemistry; TNBC: triple-negative breast carcinoma; SBR: Scarf-Bloom-Richardson; NPI: Nottingham prognostic index.
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