| | Gene network | Top diseases and functions | Genes involved | Number of genes |
| | 1 | Energy production, lipid metabolism, small molecule biochemistry | ACADL, ACADVL, CAT, CIDEC, CPT1A, EHHADH, FABP1, FABP2, GALM, HADHA, HADHB, mir-154, MT-CO1, PDK4, PKLR, PNPLA2, PRKAA1, PRKAB1, SLC22A1, SLC22A5, Tnfrsf22/Tnfrsf23, VASP | 22 | | 2 | Cellular development, cellular growth and proliferation, embryonic development | ABCB1, ACTA1, AHNAK, ATAD2, BAG2, CASP3, CD4, CIRBP, CST6, DES, DHRS9, DIAPH3, EDN1, GLUD1, MMRN1, PINK1, PPA1, TNFRSF12A | 18 | | 3 | Cellular movement, cellular assembly and organization, connective tissue development and function | ALOX15, BMP3, BMP4, BOK, CTGF, CYR61, ENAH, FBLN2, ITGA5, LOX, PLOD2, PRF1, PRR7, SSPN | 14 | | 4 | Amino acid metabolism, small molecule biochemistry, cell morphology | CBS/CBSL, CTH, ITGB1, Ldha/RGD1562690, LDLR, PADI2, PDIA4, PDIA6, RAB9A, RRM2, SLC2A12, SOD3, STARD3 | 13 | | 5 | Cellular assembly and organization, DNA replication, recombination, and repair, cell cycle | CDC6, CKAP2, DEPTOR, DLGAP5, EIF4E, FAM110C, LOXL2, MAPK6, MCOLN1, PNRC1, RETSAT, TK1, YPEL3 | 13 | | 6 | Neurological disease, organismal injury and abnormalities, cancer | ADGRL3, ALDH6A1, CEP55, CX3CR1, GLYR1, MPST, NT5DC3, RCN3, SPAG5, Sult1a1, TRIP13, UGGT1, ZNF24 | 13 | | 7 | Cancer, cell cycle, cell death, and survival | Ankh, ATG13, BLZF1, CADM3, CDCA8, CEACAM4, KIF20A, OXA1L, SEPW1, SLC25A20, SLC2A12, TUBAL3 | 12 | | 8 | Lipid metabolism, molecular transport, small molecule biochemistry | EPHX1, FA2H, RAB11B, REEP6, RTP4, SLC51B, TAS1R2, TSPAN12, ZNF750 | 9 | | 9 | Cellular function and maintenance, connective tissue development and function, skeletal and muscular system development and function | CREBRF, FN1, HOXA7, MYH10, PPP1CB, PTGR1, SMC2, TMEM117 | 8 | | 10 | Lipid metabolism, nucleic acid metabolism, small molecule biochemistry | ELOVL6, HPGDS, LGALS9B, PGK1, WT1 | 5 |
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