Effect of Huangqin Tang on Colonic Gene Expression in Rats with Ulcerative Colitis

Table 4

List of HQT-regulated genes screened in terms of the “degree”.

Gene name	Description	Location	Style	Degree	Biological process
ITGB1	Integrin, beta 1	Plasma membrane	Up	25	G1/S transition of mitotic cell cycle
FN1	Fibronectin 1	Extracellular space	Up	23	Ossification
ITGA5	Integrin, alpha 5 (fibronectin receptor, alpha polypeptide)	Plasma membrane	Up	15	Cell-substrate junction assembly
CD4	Cd4 molecule	Plasma membrane	Down	13	Cytokine production
VASP	Vasodilator-stimulated phosphoprotein	Plasma membrane	Up	13	Neural tube closure
CTH	Cystathionase (cystathionine gamma-lyase)	Cytoplasm	Down	11	Glutathione metabolic process
RRM2	Ribonucleotide reductase M2	Nucleus	Up	11	Mitotic cell cycle
CTGF	Connective tissue growth factor	Extracellular space	Up	10

Note: “degree” represents the interaction information between genes. In general, the larger values suggested more associations.