Circ_0078767 Inhibits the Progression of Non-Small-Cell Lung Cancer by Regulating the GPX3 Expression by Adsorbing miR-665

Figure 2

The functional roles of circ_0078767 on proliferation, migration, and invasion in NSCLC cells. (a) The expression level of circ_0078767 was determined by qRT-PCR assay in A549 and HCC827 cells transfected with si-NC or si-circ_0078767#1, si-circ_0078767#2, and si-circ_0078767#3. (b) Colony formation assay was used to assess proliferation of transfected A549 and HCC827 cells. (c, d) The role of circ_0078767 knockdown on cell migration and invasion was monitored by transwell assay. (e, f) Glucose consumption and lactate production were measured to assess glycolysis metabolism using commercial kits. (g, h) The protein expression level of MMP9 and HK2 was tested by Western blot analysis in transfected A549 and HCC827 cells. .

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