Research Article
Circ_0078767 Inhibits the Progression of Non-Small-Cell Lung Cancer by Regulating the GPX3 Expression by Adsorbing miR-665
Figure 5
GPX3 is the direct target of miR-665. (a) The complementary sequences between miR-665 and GPX3 were shown. (b) Dual-luciferase reporter assays were performed to confirm the association between miR-665 and GPX3 3UTR. (c, e) The expression of GPX3 in NSCLC tissues () and cells was tested by qRT-PCR. (d, f) Western blot examined the protein level of GPX3 in NSCLC tissues () and cells. (g) Western blot was used to detect the expression of GPX3 in transfected A549 and HCC827 cells. .
(a) |
(b) |
(c) |
(d) |
(e) |
(f) |
(g) |