Correlation between LSM1 Expression and Clinical Outcomes in Glioblastoma and Functional Mechanisms

Figure 5

Correlation between LSM1 expression and immune cell infiltration in GBM using TCGA dataset. (a) Analysis of LSM1 expression reveals correlations with immune cell infiltration in GBM. Representative correlations are shown: (b) negative correlation with TFH cell infiltration; (c) negative correlation with CD56bright cell infiltration; (d) positive correlation with macrophage infiltration; and (e) positive correlation with Th2 cell enrichment. These findings indicate that LSM1 expression in GBM is linked to distinct patterns of immune cell infiltration, shed light on the potential immunoregulatory role of LSM1 in the GBM tumor microenvironment, and provide insights into its impact on immune cell interactions.

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