Correlation between LSM1 Expression and Clinical Outcomes in Glioblastoma and Functional Mechanisms

Table 2

Survival analysis of glioma patients.

Characteristics	Cases ()	Univariate analysis		Multivariate analysis
		Hazard ratio (95% CI)	value	Hazard ratio (95% CI)	value
Age (years old)	698		<0.001
≤60	555	Reference		Reference
>60	143	4.696 (3.620-6.093)	<0.001	2.054 (1.541-2.737)	<0.001
Gender	698		0.071
Female	297	Reference
Male	401	1.250 (0.979-1.595)	0.073
IDH status	688		<0.001
Wild type	246	Reference		Reference
Mutation	442	0.116 (0.089-0.151)	<0.001	0.183 (0.132-0.253)	<0.001
1p/19q codeletion	691		<0.001
Noncodel	520	Reference		Reference
Codel	171	0.225 (0.147-0.346)	<0.001	0.634 (0.390-1.028)	0.065
LSM1	698		<0.001
Low	348	Reference		Reference
High	350	2.878 (2.217-3.735)	<0.001	1.473 (1.114-1.949)	0.007

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