Genomic Regions and Candidate Genes Associated with Milk Production Traits in Holstein and Its Crossbred Cattle: A Review

Table 1

Candidate genes and genomic regions for MY in Holstein and its crossbreds.

SNP name	Gene	Chromosome	Breed	Number of cattle	Authors
rs41577598	BAIAP2	19	Canadian Holstein	462	[25]
rs41592943	GUCY2C	5
rs41608371	FBLN5	21
rs41632222	LOC512656	14
rs41633664	LOC785291	1
rs41643471	LOC508029	1
rs41655901	GALNT6	5
rs41656714	LOC407194	5
rs41658330	FANCC	8
rs43709850	LOC511740	3
rs42517915	LOC788012	9	Chinese Holstein	2,093	[21]
rs43030751	LOC100139865	9
rs41654691	INXA1	8	U.S. Holstein	1,654	[19]
rs42300745	TMX4	13
rs42586116	PTBP2	3
rs42586854	PTBP2	3
rs42725189	PTBP2	3
rs43408337	ULOC781500	4
rs109289569	L00531776	14
rs110384096	C-ICNG5	19
rs110944623	PIGN	24
rs41568120	PLCB1	13
rs41643761	SLC25A2 I	21
rs42914124	LOCI00140505	10
rs109104203	INO80	10	Portuguese Holstein	526	[24]
rs109832473	CACNB2	13
rs109942798	LOC525149	12
rs110323635	MAPK15	14
rs110476141	AQP4	24
rs41580384	CACNB2	13
rs41659095	GPAM	26
rs43186715	LOC525149	12
rs43272177	MARS	1
rs41640548	ATP11B	1	Chinese Holstein	445	[18]
rs110281536	EEF2K	25
rs41774442	GNA14	15	Thai Crossbreds	36	[8]
rs41776130	GNA14	15
rs41776828	LRRC4C	15
rs41779510	GNA14	15
rs41796094	GNA14	8
rs43705173	STAT1	2	Italian Holstein	45,115	[23]
rs41631082	ECI2	23	Russian Crossbreds	477	[9]
rs43364576	MACF1	3
rs109295123	SPOPL, HNMT	2
rs110748809	DTX1	17
rs110425841	PODXL2	22	Colombian Holstein	150	[10]
rs110718748	ANKS1B	5
rs41607880	TMEM229A	4
rs41913085	VIT	11
rs43483670	MAPK10	6
rs110482506	GHR	20	US Holstein	294,079	[26]
rs110527224	GC	6
rs137431035	PTGER4	20
rs41938455	C6	20
ss2019489562	UGDH	6
rs41613423	CYP7B1	14	Chinese Holstein	295	[11]
rs474736745	PAIP1	20	French Holstein	6321	[13]
rs109355809	U6	14	Brazilian Crossbreds	337	[16]
rs109381761	SLC51A	1
rs109704754	U6	18
rs110565520	CD47	1
rs41570140	FBXO11	11
rs41642215	BET1	4
rs41647684	BMPR1A	28
rs42123132	SSBP2	7
rs42215728	SLC24A2	8
rs42271	SLC24A2	8
rs42290054	CDH12	20
rs42490796	EDIL3	7
rs42583510	FBXO11	11
rs42900126	ANXA5	6
rs43424124	NUB1	4
rs108973652	IREB2	21
rs108977582	ITGB1BP1	11
rs108982955	TMEM247	11
rs109009656	MAP1B	20
rs109099963	FAM135B	14
rs109176086	KHDRBS3	14
rs109327460	SLC35B3	23
rs109840333	SLIT3	20
rs109854193	FST	20
rs109901641	FAM114A2	7
rs109912809	U6	7
rs109984167	HSPB3	20
rs110192732	HES1	1
rs29021936	ELAVL2	8
rs41657410	PAM	7
rs41919419	TANC2	19
rs42040508	MBP	24
rs42343030	GCNT2	23
rs42615382	TEX35	16
rs42674867	5S_rRNA	18
rs42934321	LAMA3	24
rs43419957	WDR86	4
rs110535430	MARCHF10	19
rs110632003	GRID2	6
rs110775601	NPFFR2	6	Korean Holstein	2780	[17]
rs135477609	ADRA1B	7
rs110527224	SLC4A4	6
rs517703887	PKHD1	23
rs524049037	GFRA2	8
rs108962265	PITRM1	1	Chinese Holstein	999	[7]
rs110246034	PRMT6	3