The Potential Mechanism of Curcumin in Treating Oral Squamous Cell Carcinoma Based on Integrated Bioinformatic Analysis

Figure 8

Protein-protein interaction network. (a) The protein-protein interaction network of the candidate curcumin-OSCC interaction genes. The network nodes represent proteins, while the edges represent interactions between the proteins. Different colors of the edges indicate various types of evidence supporting the interactions. (b) The top 10 hub genes identified by the maximal clique centrality algorithm include VEGFA, AKT1, TNF, HIF1A, EGFR, JUN, STAT3, MMP9, EGF, and MAPK3.

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