Multidisciplinary Pharmacotherapeutic Options for Nonalcoholic Fatty Liver Disease

Table 1

List of drugs and agents as candidates for the treatment of NAFLD.

Insulin sensitizers
Metformin (Biguanide)
Thiazolidines (Pioglitazone, Rosiglitazone)
Antioxidants
Vitamin E
Vitamin C
Polyphenols (Resveratrol, etc.)
Hepatocyte-protective agents
Ursodeoxycholic acid
n-3 polyunsaturated fatty acids (EPA and DHA)
Antidyslipidemia
Statins
Fibrates
NPC1L1 inhibitors (ezetimibe)
RAS blockers
Angiotensin II receptor blockers
Angiotensin-converting enzyme inhibitors
Antialdosterone (spironolactone and eplerenone)
Renin inhibitor (aliskiren)
Incretin-related agents
GLP-1 agonists/analogs (exenatide and liraglutide)
DPP-4 inhibitors (sitagliptin and vildagliptin)
Antiobesity drugs
Orlistat
Sibutramine
Mazindol