Enhanced Antitumor Activity with Combining Effect of mTOR Inhibition and Microtubule Stabilization in Hepatocellular Carcinoma

Table 1

Average tumor volume and tumor weight during treatments in Hep3B xenograft model.

Treatments	Average tumor volume (mm^3)		Average tumor weight (𝜇g)
	Week 1	Week 2	End of experiment
Veh	122.66±15.73	352.97±40.47	434.70±60.43
Eve	81.75±9.32	218.56±25.25	308.60±44.10
	(^∗𝑃<0.05)	(^∗𝑃<0.05)	(𝑃=0.11)
Pat	92.40±12.03	239.41±33.81	346.10±56.76
	(𝑃=0.14)	(^∗𝑃<0.05)	(𝑃=0.29)
Eve/Pat	65.14±8.62	138.57±16.57	228.10±37.20
	(^∗∗𝑃<0.01)	(^∗∗∗𝑃<0.001)	(^∗∗𝑃<0.01)

^∗𝑃<0.05 versus vehicle control group; ^∗∗𝑃<0.01 versus vehicle control group; ^∗∗∗𝑃<0.001 versus vehicle control group.