Research Article
Role of High-Density Lipoprotein Cholesterol (HDL-C) as a Clinical Predictor of Decompensation in Patients with Chronic Liver Disease (CLD)
Table 1
Distribution of variables among patients with decompensation events on follow-up as compared to patients with decompensation.
| | Baseline characteristics of the population | Total |
| | Mean age (, years) | | | Gender distribution ( (%)) | | | Male | 147 (86.5) | | Female | 23 (13.5) | | Median duration of CLD at recruitment (days) | 1121 | | Etiology of CLD ( (%)) | | | Alcohol | 74 (43.5) | | Viral hepatitis | 11 (6.4) | | Cryptogenic | 85 (50) | | Comorbidities ( (%)) | | | Diabetes mellitus | 110 (64.7) | | Systemic hypertension | 51 (30) | | Coronary artery disease | 19 (11.2) | | Chronic kidney disease | 30 (17.6) | | Child status ( (%)) | | | Child A | 37 (21.8) | | Child B | 32 (18.8) | | Child C | 101 (59.4) | | Mean MELD score () | | | Past history of complications of CLD ( (%)) | | | Varices on endoscopy | 126 (74.11) | | Ascites | 95 (55.88) | | Hepatic encephalopathy | 44 (25.88) | | Variceal bleed | 41 (24.11) | | Laboratory parameters: () | | | Total cholesterol | | | High-density lipoprotein | | | Low-density lipoprotein | | | Total leucocyte count | | | Platelet count | | | Creatinine | | | Sodium | | | Potassium | | | Albumin | | | INR | | | C-reactive protein | | | Neutrophil-lymphocyte ratio (NLR) | | | Total decompensation events at follow-up ( (%)) | 97 (57.05) | | Ascites | 67 (69.07) | | Hepatic encephalopathy | 41 (42.26) | | Hepatorenal syndrome | 45 (46.39) | | Variceal bleed | 20 (20.61) | | Mortality ( (%)) | 43 (25.3) |
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Abbreviations: CLD: chronic liver disease; MELD score: model for end-stage liver disease; INR: international normalized ratio.
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