Clinical Study

Increased Nitric Oxide and Attenuated Diastolic Blood Pressure Variability in African Americans with Mildly Impaired Renal Function

Table 2

Mean BP levels from office and ABPM measurements in normal and mildly impaired renal function groups.

Normal renal functionMildly impaired renal function
VariableGFR > 90 mL/min per 1.73 m2 ( )GFR 60–89 mL/min per 1.73 m2 ( )

Office BP
 SBP (mmHg)127.3 ± 2.5122.7 ± 2.8
 DBP (mmHg)81.1 ± 1.7 76.1 ± 2.9*
ABPM
 24-hr SBP (mmHg)127.1 ± 2.6126.4 ± 3.0
 24-hr DBP (mmHg)80.3 ± 1.976.4 ± 2.3
 24-hr MAP (mmHg)96.5 ± 1.993.7 ± 2.3
 24-hr HR (beats/min)75.1 ± 2.472.3 ± 2.1
 Awake SBP (mmHg)128.5 ± 2.9129.0 ± 3.1
 Awake DBP (mmHg)81.7 ± 1.978.9 ± 2.5
 Awake MAP (mmHg)97.8 ± 2.096.3 ± 2.5
 Awake HR (beats/min)77.2 ± 2.573.8 ± 2.3
 Sleep SBP (mmHg)117.0 ± 2.2116.1 ± 2.5
 Sleep DBP (mmHg)70.3 ± 1.966.4 ± 1.9
 Sleep MAP (mmHg)86.7 ± 1.983.4 ± 1.8
 Sleep HR (beats/min)67.3 ± 2.766.0 ± 2.2
 Dip SBP (%)8.8 ± 1.2 9.8 ± 1.4
 Dip DBP (%)13.8 ± 1.515.4 ± 2.3

Values are expressed as means ± SEM. ABPM, ambulatory blood pressure monitoring; BP, blood pressure; DBP, diastolic blood pressure; GFR, glomerular filtration rate; HR, heart rate; MAP, mean arterial pressure; SBP, systolic blood pressure.
*Denotes significant difference between groups; .