Feasibility of Screening Primary Aldosteronism by Aldosterone-to-Direct Renin Concentration Ratio Derived from Chemiluminescent Immunoassay Measurement: Diagnostic Accuracy and Cutoff Value

Figure 1

Flowchart of the study. 450 hypertensive patients with suspected PA were enrolled. After screening and confirmatory tests, 386 patients were diagnosed with PH and 64 patients with PA. PH: primary hypertension; PA: primary aldosteronism; RIA: radioimmunoassay; CLIA: chemiluminescent immunoassay; : plasma aldosterone concentration measured by radioimmunoassay; ivSLT: intravenous saline loading test.