Chronic NO Restriction in Hypertensive Rats Increases Abdominal but Not Thoracic Aortic Intrinsic Stiffness via an Augmentation in Profibrotic Materials

Figure 2

Mean blood pressure (MBP) and stiffness index are compared in the three groups of rats. Black bars: spontaneously hypertensive rats treated with L-NAME (SHRLN), grey bars: SHR without treatment, and white bars: normotensive WKY. Thoracic aorta (left graph) and abdominal aorta (right graphs) parameters are shown. A: SHRLN, parameters at basal pressure, and n= 8; B: SHRLN n=5, at BP matched with that of SHR n=6; C: both SHRLN n=7 and SHR n=6 at BP matched with that of WKY n=6. N are similar at TA and AA except n=5 for WKY at AA. One way ANOVA and Tukey posttest comparison: : p<0.05 compared to WKY and #: p<0.05 compared to SHR.