Research Article
Longitudinal Average Glucose Levels and Variance and Risk of Stroke: A Chinese Cohort Study
Table 2
Risk of incident stroke associated with average glucose level (N = 12,321).
| | | Average glucose level (mg/dl) | for trend | | 80–89.9 | 90–99.9 | 100–109.9 | 110–125.9 | 126–139.9 | 140- |
| | Total stroke | | | | | | | | | Events, n (%) | 5 (2.07) | 97 (1.90) | 105 (2.18) | 30 (2.94) | 27 (3.55) | 15 (4.01) | | | Model 1 | 0.73 (0.32–1.68) | 1 | 1.12 (0.85–1.48) | 1.46 (0.97–2.20) | 1.99 (1.30–3.05) | 2.31 (1.34–3.98) | 0.0007 | | Model 2 | 0.70 (0.31–1.61) | 1 | 1.18 (0.9–1.55) | 1.40 (0.92–2.11) | 1.98 (1.29–3.03) | 2.18 (1.26–3.77) | <0.0001 | | Model 3 | 0.74 (0.32–1.69) | 1 | 1.11 (0.84–1.46) | 1.29 (0.85–1.95) | 1.78 (1.16–2.75) | 1.89 (1.09–3.29) | 0.0009 | | Nonfatal stroke | | | | | | | | | Events, n (%) | 3 (1.24) | 42 (0.82) | 49 (1.02) | 17 (1.67) | 15 (1.97) | 7 (1.87) | | | Model 1 | 1.03 (0.31–3.22) | 1 | 1.24 (0.82–1.86) | 1.73 (0.98–3.04) | 2.38 (1.32–4.29) | 2.23 (1.01–4.97) | 0.0008 | | Model 2 | 1.01 (0.31–3.28) | 1 | 1.25 (0.83–1.99) | 1.75 (1.00–3.09) | 2.41 (1.33–4.34) | 2.19 (0.98–4.88) | 0.0009 | | Model 3 | 1.06 (0.33–3.42) | 1 | 1.17 (0.77–1.78) | 1.60 (0.90–2.82) | 2.16 (1.19–3.93) | 1.87 (0.83–4.22) | 0.0067 | | Fatal stroke | | | | | | | | | Events, n (%) | 2 (0.83) | 55 (1.08) | 56 (1.16) | 13 (1.27) | 12 (1.58) | 8 (2.14) | | | Model 1 | 0.53 (0.13–2.16) | 1 | 1.02 (0.7–1.48) | 1.22 (0.66–2.23) | 1.64 (0.88–3.06) | 2.4 (1.14–5.04) | 0.0096 | | Model 2 | 0.42 (0.1–1.74) | 1 | 1.09 (0.75–1.58) | 1.05 (0.57–1.94) | 1.5 (0.8–2.8) | 2.13 (1.01–4.5) | 0.0245 | | Model 3 | 0.43 (0.11–1.79) | 1 | 1.02 (0.7–1.49) | 0.98 (0.53–1.81) | 1.34 (0.71–2.54) | 1.85 (0.86–3.96) | 0.0871 |
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Model 2, adjusted for age, sex; Model 3, adjusted for age, sex, education, smoke, drink, sport, BMI, systolic blood pressure, total cholesterol.
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