Research Article
Longitudinal Average Glucose Levels and Variance and Risk of Stroke: A Chinese Cohort Study
Table 3
Risk of incident stroke associated with average glucose level over the preceding 5 years among participants without diabete (N = 11,310).
| | | Average glucose level (mg/dl) | for trend | | 80–89.9 | 90–99.9 | 100–109.9 | 110–125.9 | 126–139.9 | 140- |
| | Total stroke | | | | | | | | | Events, n (%) | 5 (2.07) | 96 (1.88) | 104 (2.18) | 27 (3.21) | 7 (2.33) | 5 (8.20) | | | Model 1 | 0.74 (0.3–1.83) | 1 | 1.11 (0.84–1.47) | 1.53 (1–2.35) | 1.27 (0.59–2.74) | 4.24 (1.72–10.44) | 0.0050 | | Model 2 | 0.68 (0.28–1.67) | 1 | 1.17 (0.88–1.54) | 1.49 (0.97–2.3) | 1.25 (0.58–2.69) | 4.07 (1.65–10.05) | 0.0045 | | Model 3 | 0.7 (0.28–1.73) | 1 | 1.1 (0.83–1.46) | 1.39 (0.9–2.14) | 1.15 (0.53–2.5) | 3.66 (1.47–9.08) | 0.0205 | | Nonfatal stroke | | | | | | | | | Events, n (%) | 3 (1.24) | 42 (0.82) | 49 (1.03) | 15 (1.78) | 4 (1.33) | 1 (1.64) | | | Model 1 | 0.84 (0.26–2.72) | 1 | 1.25 (0.83–1.88) | 1.78 (0.99–3.21) | 1.44 (0.52–4.03) | 1.56 (0.21–11.33) | 0.0586 | | Model 2 | 0.88 (0.27–2.85) | 1 | 1.30 (0.86–1.96) | 1.84 (1.02–3.33) | 1.46 (0.52–4.07) | 1.61 (0.22–11.70) | 0.0475 | | Model 3 | 0.90 (0.28–2.91) | 1 | 1.24 (0.82–1.88) | 1.72 (0.95–3.13) | 1.38 (0.49–3.87) | 1.53 (0.21–11.22) | 0.0912 | | Fatal stroke | | | | | | | | | Events, n (%) | 2 (0.83) | 54 (0.83) | 55 (1.15) | 12 (1.43) | 3 (1.00) | 4 (6.56) | | | Model 1 | 0.54 (0.13–2.23) | 1 | 1.02 (0.7–1.49) | 1.3 (0.69–2.43) | 1.09 (0.34–3.51) | 7.19 (2.59–19.98) | 0.0345 | | Model 2 | 0.43 (0.11–1.78) | 1 | 1.09 (0.75–1.59) | 1.14 (0.6–2.14) | 0.99 (0.31–3.19) | 5.92 (2.12–16.59) | 0.0481 | | Model 3 | 0.45 (0.11–1.85) | 1 | 1.01 (0.69–1.49) | 1.06 (0.56–2) | 0.88 (0.27–2.85) | 5 (1.77–14.15) | 0.1295 |
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Model 2, adjusted for age, sex; Model 3, adjusted for age, sex, education, smoke, drink, sport, BMI, systolic blood pressure, total cholesterol.
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