Research Article
Longitudinal Average Glucose Levels and Variance and Risk of Stroke: A Chinese Cohort Study
Table 4
Risk of incident stroke associated with variance (N = 11,310).
| | | Standard deviation | for trend | | Quartile 1 (<5.91) | Quartile 1 (5.91 to 8.9) | Quartile 1 (8.91 to 13.83) | Quartile 1 (>13.83) |
| | Total stroke | | | | | | | Events, n (%) | 42 (1.68) | 48 (1.92) | 40 (1.60) | 75 (3.00) | | | HR | 1 | 1.25 (0.85–1.84) | 1.72 (1.15–2.59) | 1.83 (1.07–3.11) | 0.001 | | Nonfatal stroke | | | | | | | Events, n (%) | 16 (0.64) | 33 (1.32) | 26 (1.04) | 40 (1.6) | | | HR | 1 | 1.47 (0.87–2.47) | 1.98 (1.14–3.43) | 1.71 (0.79–3.72) | 0.008 | | Fatal stroke | | | | | | | Events, n (%) | 26 (1.04) | 15 (0.60) | 14 (0.56) | 35 (1.40) | | | HR | 1 | 1.13 (0.66–1.95) | 1.34 (0.74–2.45) | 2.31 (1.19–4.48) | 0.0198 | | Participants without diabetes | | | | | | | Total stroke | | | | | | | Events, n (%) | 42 (1.7) | 47 (1.9) | 39 (1.63) | 46 (2.56) | | | HR | 1 | 1.33 (0.89–2.00) | 1.11 (0.52–2.36) | 3.49 (1.43–8.55) | 0.0246 | | Nonfatal stroke | | | | | | | Events, n (%) | 26 (1.05) | 32 (1.3) | 25 (1.04) | 23 (1.28) | | | HR | 1 | 1.56 (0.90–2.70) | 1.25 (0.46–3.41) | 1.42 (0.2–10.23) | 0.2053 | | Fatal stroke | | | | | | | Events, n (%) | 16 (0.65) | 15 (0.60) | 14 (0.58) | 23 (1.28) | | | HR | 1 | 1.24 (0.70–2.17) | 0.90 (0.28–2.85) | 6.38 (2.55–15.95) | 0.016 |
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Adjusted for age, sex, education, smoke, drink, sport, BMI, systolic blood pressure, total cholesterol.
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