Research Article

Brachial-Ankle Pulse Wave Velocity Predicts New-Onset Hypertension and the Modifying Effect of Blood Pressure in a Chinese Community-Based Population

Table 1

Baseline characteristics of all eligible participants.

VariablesTotal (n = 1849)Baseline SBP, mmHg value
<120 (n = 663)≥120 − <130 (n = 676)≥130 (n = 510)

Age, year54.18 ± 7.5452.60 ± 6.7954.25 ± 7.2356.15 ± 8.36<0.001
Males, n (%)582 (31.48%)149 (22.47%)243 (35.95%)190 (37.25%)<0.001
BMI, kg/m225.28 ± 3.2424.53 ± 3.1125.56 ± 3.2725.87 ± 3.19<0.001
SBP, mmHg122.98 ± 9.76112.43 ± 6.06124.70 ± 2.87134.40 ± 2.81<0.001
DBP, mmHg71.57 ± 7.6167.16 ± 6.2873.04 ± 6.5575.33 ± 7.73<0.001
baPWV, cm/s1498.20 ± 276.691381.52 ± 221.811508.78 ± 263.421635.88 ± 291.68<0.001
Total cholesterol, mmol/L5.34 ± 0.985.31 ± 0.955.34 ± 0.995.38 ± 1.010.449
Triglyceride, mmol/L1.19 (0.86–1.78)1.11 (0.82–1.60)1.24 (0.87–1.84)1.31 (0.91–1.82)<0.001
HDL-cholesterol, mmol/L1.48 ± 0.391.54 ± 0.401.46 ± 0.381.43 ± 0.39<0.001
LDL-cholesterol, mmol/L3.25 ± 0.823.20 ± 0.803.28 ± 0.823.30 ± 0.860.083
Fasting glucose, mmol/L5.87 ± 1.525.71 ± 1.615.87 ± 1.406.09 ± 1.53<0.001
2 h-PG in OGTT, mmol/L7.75 ± 3.517.32 ± 3.377.65 ± 3.378.43 ± 3.77<0.001
eGFR, ml/min/1.73 m297.33 ± 11.2199.00 ± 10.4296.80 ± 11.5995.87 ± 11.42<0.001
Current smoking, n (%)371 (20.06%)105 (15.84%)156 (23.08%)110 (21.57%)0.003
Current drinking, n (%)424 (22.93%)130 (19.61%)171 (25.30%)123 (24.12%)0.035
Prevalence of disease, n (%)
 Diabetes mellitus279 (15.09%)72 (10.86%)105 (15.53%)102 (20.00%)<0.001
 Dyslipidemia1230 (66.52%)424 (63.95%)461 (68.20%)345 (67.65%)0.212
 Cardiovascular disease103 (5.57%)31 (4.68%)34 (5.03%)38 (7.45%)0.090
Medication, n (%)
 Hypoglycemic agents112 (6.06%)36 (5.44%)38 (5.63%)38 (7.45%)0.301
 Lipid-lowering agents97 (5.28%)31 (4.70%)36 (5.36%)30 (5.94%)0.642

baPWV, brachial-ankle pulse wave velocity; BMI, body mass index; SBP, systolic blood pressure; DBP, diastolic blood pressure; eGFR, estimated glomerular filtration rate; HDL, high-density lipoprotein; LDL, low-density lipoprotein; 2 h-PG in OGTT: 2-hour postload glucose in oral glucose tolerance test. Median (interquartile range).