Brachial-Ankle Pulse Wave Velocity Predicts New-Onset Hypertension and the Modifying Effect of Blood Pressure in a Chinese Community-Based Population

Table 2

Multivariate regression for the effect of baseline baPWV on the development of incident hypertension.

Variables	N	Incidence, %	Crude model		Adjusted model 1		Adjusted model 2
			OR (95% CI)	value	OR (95% CI)	value	OR (95% CI)	value
baPWV continuous, per 1 m/s increase
	1849	248 (13.41%)	1.23 (1.17, 1.28)	<0.001	1.22 (1.15, 1.28)	<0.001	1.14 (1.07, 1.20)	<0.001
baPWV categories, cm/s
Q1 (<1311)	466	21 (4.59%)	1 (reference)		1 (reference)		1 (reference)
Q2 (≥1311 − <1451)	462	45 (9.74%)	2.25 (1.32, 3.83)	0.003	2.15 (1.26, 3.68)	0.005	1.67 (0.95, 2.94)	0.076
Q3 (≥1451 − <1622)	466	72 (15.45%)	3.80 (2.30, 6.30)	<0.001	3.50 (2.09, 5.87)	<0.001	2.05 (1.18, 3.55)	0.010
Q4 (≥1622)	463	110 (23.76%)	6.48 (3.98, 10.56)	<0.001	5.49 (3.24, 9.28)	<0.001	2.72 (1.54, 4.78)	<0.001
for trend				<0.001		<0.001

baPWV, brachial-ankle pulse wave velocity; OR, odds ratio; CI, confidence interval. Model 1, adjusted for age and sex; Model 2, adjusted for variables in model 1 and body mass index, current smoking, current drinking, baseline systolic blood pressure and estimated glomerular filtration rate, diabetes mellitus, dyslipidemia, history of cardiovascular disease, hypoglycemic agents, and lipid-lowering agents.