The Effect of Chronic and Inhospital Exposure to Renin-Angiotensin System Inhibitors on the Outcome and Inflammatory State of Coronavirus Disease 2019 Adult Inpatients

Table 2

Odds ratios for measured outcomes between RASi and non-RASi groups as a function of the patients’ demographic characteristics and comorbid conditions.

	Crude model			Adjusted model
	Coef.	OR (95% CI)		Coef.	OR (95% CI)
Death	0.21	1.24 (0.66–2.31)	0.500	- 0.42	0.66 (0.31–1.40)	0.279
ARDS/ALI	0.11	1.12 (0.67–1.86)	0.676	0.10	1.11 (0.66–1.87)	0.698
ICU admission	0.10	1.11 (0.67–1.84)	0.686	0.06	1.06 (0.63–1.79)	0.828
IMV need	0.03	1.03 (0.58–1.84)	0.917	0.01	1.01 (0.56–1.83)	0.962

ORs and values were calculated with logistic regression analysis. Multivariable OR was adjusted as follows: death: age, high blood pressure, cardiovascular disease, and chronic obstructive pulmonary disease; ARDS/ALI: sex; ICU admission: sex; and chronic obstructive pulmonary disease and IMV: sex. ARDS/ALI, acute respiratory distress syndrome/acute lung injury; CI, confidence interval; Coef., logistic regression coefficient; ICU, intensive care unit; IMV, invasive mechanical ventilation; OR, odds ratio; RASi, renin-angiotensin system inhibitors.