Association of the Risk of Osteoarthritis and Hypertension in the Korean Adult Population Aged 40–59 in Pre- and Postmenopausal Women: Using Korea National Health and Nutrition Examination Survey 2012–2016 Data

Table 3

Characteristics of the groups with and without hypertension according to the menopause status.

Characteristics		Total n	PreMp (n = 2,408)		value	Total n	Mp (n = 2,219)		value
			Non-HTN (n = 2,228); n (%)	HTN (n = 180); n (%)			Non-HTN (n = 1,726); n (%)	HTN (n = 493); n (%)
Age (years)	40–49	2018	1900 (94.2)	118 (5.8)	<0.001	200	174 (87.0)	26 (13.0)	<0.001
	50–59	390	328 (84.1)	62 (15.9)		2019	1552 (76.9)	467 (23.1)
Smoking	Smoking	124	112 (90.3)	12 (9.7)	0.613	113	86 (76.1)	27 (23.9)	0.801
	Past	99	92 (92.9)	7 (7.1)		69	52 (75.4)	17 (24.6)
	Nonsmoking	2176	2017 (92.7)	159 (7.3)		2026	1579 (77.9)	447 (22.1)
Alcohol consumption	No	378	349 (92.3)	29 (7.7)	0.574	434	335 (77.2)	99 (22.8)	0.097
	<1/m^a	903	837 (92.7)	66 (7.3)		835	673 (80.6)	162 (19.4)
	>1/m^a	877	822 (93.7)	55 (6.3)		580	441 (76.0)	139 (24.0)
OA	No	2303	2142 (93.0)	161 (7.0)	<0.001	1845	1462 (79.2)	383 (20.8)	<0.001
	Yes	105	86 (81.9)	19 (18.1)		374	264 (70.6)	110 (29.4)
BMI (Kg/m^2)	Low (<18.5)	96	95 (99.0)	1 (1.0)	<0.001	50	49 (98.0)	1 (2.0)	<0.001
	Normal (18.5 to <25)	1668	1578 (94.6)	90 (5.4)		1458	1228 (84.2)	230 (15.8)
	Obesity (≥25)	639	550 (86.1)	89 (13.9)		709	447 (63.0)	262 (37.0)
Clinical			Mean (SD)	Mean (SD)			Mean (SD)	Mean (SD)
	Age	2408	45.3 (3.7)	47.8 (3.8)	<0.001	2219	54.1 (3.6)	55.2 (3.1)	<0.001
	EQ-5D	2406	1.0 (0.1)	1.0 (0.1)	0.054	2219	0.9 (0.1)	0.9 (0.1)	0.018
	SBP (mmHg)	2401	111.0 (14.4)	124.3 (14.4)	<0.001	2217	115.7 (15.7)	128.4 (16.6)	<0.001
	DBP (mmHg)	2401	73.7 (9.5)	81.8 (9.9)	<0.001	2217	75.2 (9.3)	81.2 (9.9)	<0.001
	FBS (mg/dL)	2316	95.3 (17.7)	104.6 (28.0)	<0.001	2118	98.6 (21.6)	106.9 (35.0)	<0.001
	TG (mg/dL)	2317	106.7 (74.2)	146.9 (104.4)	<0.001	2118	126.1 (87.7)	152.2 (144.8)	<0.001
	Chol (mg/dL)	2317	191.2 (32.3)	194.1 (37.1)	0.325	2118	207.3 (36.4)	195.4 (37.0)	<0.001
	HDL-C (mg/dL)	2317	55.7 (12.5)	51.5 (11.8)	<0.001	2118	54.4 (12.6)	51.1 (12.0)	<0.001
	AST (IU/L)	2317	19.2 (8.6)	22.7 (15.2)	0.003	2118	22.6 (9.4)	25.0 (18.5)	0.006
	ALT (IU/L)	2317	16.5 (13.8)	23.3 (22.8)	<0.001	2118	20.2 (13.0)	24.7 (18.9)	<0.001
	CREA (mg/dL)	2317	0.7 (0.1)	0.7 (0.2)	0.144	2118	0.7 (0.1)	0.7 (0.4)	<0.001

OA: osteoarthritis; Mp: menopause; HTN: hypertension; SD: standard deviation; EQ-5D: euro quality of life-5 dimensions; SBP: systolic blood pressure; DBP: diastolic blood pressure; FBS: fasting blood sugar; TG: triglyceride; Chol: cholesterol; HDL-C: high-density lipoprotein cholesterol; AST: aspartate aminotransferase; ALT: alanine aminotransferase; CREA: creatinine. ^a1/m = 1 glass per month.