Positive Associations between Adipocyte Fatty Acid-Binding Protein Level and Central Arterial Stiffness in Peritoneal Dialysis Patients
Table 3
Correlation between carotid-femoral pulse wave velocity levels and clinical variables among 76 peritoneal dialysis patients.
Variables
Carotid-femoral PWV (m/s)
Simple regression
Multivariate regression
r
value
Beta
Adjusted R2
value
Female
−0.140
0.228
–
–
–
Diabetes
0.173
0.135
–
–
–
Hypertension
−0.057
0.625
–
–
–
Age (years)
0.364
<0.001
0.388
0.144
<0.001
PD vintage (months)
0.226
0.049
–
–
–
Height (cm)
−0.007
0.949
–
–
–
Body weight (kg)
0.130
0.262
–
–
–
Body mass index (kg/m2)
0.149
0.198
–
–
–
Systolic blood pressure (mmHg)
0.123
0.288
–
–
–
Diastolic blood pressure (mmHg)
0.061
0.600
–
–
–
Total cholesterol (mg/dl)
0.019
0.870
–
–
–
Log-triglyceride (mg/dl)
0.082
0.481
–
–
–
Log-glucose (mg/dl)
0.284
0.013
–
–
–
Albumin (mg/dl)
−0.098
0.400
–
–
–
Blood urea nitrogen (mg/dl)
0.039
0.739
–
–
–
Creatinine (mg/dl)
−0.107
0.357
–
–
–
Total calcium (mg/dl)
0.006
0.961
–
–
–
Phosphorus (mg/dl)
−0.108
0.353
–
–
–
Log-iPTH(pg/ml)
−0.013
0.911
–
–
–
Log-CRP (mg/dl)
0.394
<0.001
–
–
–
A-FABP (ng/mL)
0.456
<0.001
0.476
0.197
<0.001
Weekly (Kt/V)
−0.153
0.188
–
–
–
Peritoneal (Kt/V)
−0.118
0.309
–
–
–
Total clearance of creatinine (l/week)
0.072
0.539
–
–
–
Peritoneal clearance of creatinine (l/week)
0.063
0.586
–
–
–
Data of triglyceride, glucose, CRP, and iPTH levels showed skewed distribution and therefore were log-transformed before analysis. Analysis of data was done using the simple regression analyses or multivariate stepwise linear regression analysis (adopted factors: PD vintage, age, log-glucose, log-CRP, and A-FABP). PD, peritoneal dialysis; A-FABP, adipocyte fatty acid binding protein; iPTH, Intact parathyroid hormone; CRP, C-reactive protein; weekly Kt/V, weekly fractional clearance index for urea. < 0.05 was considered statistically significant.
