Research Article

Trajectories of Blood Pressure in Patients with Established Coronary Artery Disease over 20 years

Table 1

Characteristics of the study group by the survey.

Survey I n = 415Survey II n = 427Survey III n = 421Survey IV n = 456Survey V n = 274 for trend

Age, years, mean (SD)57.9 (8.3)58.6 (8.1)59.9 (7.5)61.1 (6.9)62.6 (6.9)<0.001
Sex
 Men, n (%)303 (73.0)298 (69.8)300 (71.3)309 (67.8)204 (74.5)0.79
 Women, n (%)112 (27.0)129 (30.2)121 (28.7)147 (32.2)70 (25.5)
Duration of education, years, mean (SD)11.4 (3.6)11.6 (3.5)11.9 (3.3)12.1 (3.1)13.0 (3.1)<0.001
Employed, n (%)71 (17.1)75 (17.6)154 (36.6)122 (26.9)121 (44.2)<0.001
Index event
 Myocardial infarction, n (%)114 (27.5)115 (26.9)98 (23.2)154 (33.8)95 (34.7)0.007
 Unstable angina, n (%)94 (22.7)95 (22.3)112 (26.6)142 (31.1)47 (17.2)0.56
 PCI, n (%)99 (23.9)101 (23.7)134 (31.8)113 (24.8)116 (42.3)0.001
 CABG, n (%)108 (26.0)116 (27.2)77 (18.3)47 (10.3)16 (5.8)<0.001
Body mass index, mean (SD)27.5 (3.7)28.1 (4.1)28.6 (4.3)28.9 (4.4)29.2 (4.4)<0.001
Diabetes, n (%)62 (14.9)71 (16.6)128 (30.4)152 (30.3)103 (37.6)<0.001
β-Blockers, %245 (59.0)273 (63.9)366 (87.4)368 (80.7)254 (92.7)<0.001
ACE inhibitors/sartans, %190 (45.8)203 (47.5)330 (78.8)351 (77.0)244 (89.1)<0.001
 ACE inhibitors, %190 (45.8)203 (47.5)312 (74.5)302 (66.2)205 (74.8)<0.001
 Sartans, %0 (0.0)0 (0.0)22 (5.3)52 (12.5)39 (14.2)<0.001
Calcium antagonists, %119 (28.7)142 (33.3)88 (21.0)94 (20.6)76 (27.7)0.01
Diuretics, %71 (17.1)86 (21.1)134 (32.1)163 (35.8)113 (41.2)<0.001
Other, %2 (0.5)9 (2.1)10 (2.4)31 (6.8)8 (2.9)<0.001
Number of blood pressure lowering drugs, mean (SD)1.51 (0.92)1.67 (1.00)2.22 (0.89)2.23 (1.04)2.54 (0.83)<0.001

CABG, coronary artery bypass grafting; PCI, percutaneous coronary intervention.