Research Article

Fibrosis-4 Index Is Closely Associated with Arterial Damage and Future Risk of Coronary Heart Disease in Type 2 Diabetes

Table 1

Clinical characteristics of study subjects.

Clinical characteristicsMean ± SD, n (%)Range

Sex (men)163 (64.4)
Age (years)65.6 ± 10.935–86
Body mass index25.09 ± 4.5214.3–40.1
Smoking habit (current)55 (21.7)
Systolic blood pressure (mmHg)130.6 ± 16.892–181
Diastolic blood pressure (mmHg)76.4 ± 11.243–105
Hypertension195 (77.1)
Statin use147 (58.1)
PLT (×109/L)231.9 ± 60.7111–531
ALT (IU/L)24.8 ± 14.37–143
AST (IU/L)26.7 ± 21.67–232
FIB4 index1.52 ± 0.740.36–4.84
HDL-CHOL (mmol/L)1.41 ± 0.450.65–3.81
LDL-CHOL (mmol/L)2.66 ± 0.840.85–8.86
Triglyceride (mmol/L)1.55 ± 0.980.36–7.91
Uric acid (µmol/L)325.5 ± 77.859.5–630.5
eGFR (mL/min/1.73 m2)74.14 ± 25.1614.9–176.9
HbA1c (%)7.95 ± 1.885.6–18.3

SD, standard deviation; PLT, platelet; ALT, alanine aminotransferase, AST, aspartate aminotransferase; FIB4 index, fibrosis-4 index; HDL-CHOL, high-density lipoprotein cholesterol; LDL-CHOL, low-density lipoprotein cholesterol; eGFR, estimated glomerular filtration rate; HbA1c, glycosylated hemoglobin.