Fibrosis-4 Index Is Closely Associated with Arterial Damage and Future Risk of Coronary Heart Disease in Type 2 Diabetes

Table 3

Univariate or multivariate linear regression analysis predicting the association between FIB4 index, IMT, suita score, IMT calcification, and AAC grade.

Dependent variables	β-coefficient	95% confidence interval	value
(i) Univariate analysis
IMT (mm)	0.312	0.156–0.468	<0.001
Suita score	3.573	2.114–5.032	<0.001
CAC	0.183	0.103–0.263	<0.001
AAC grade	0.355	0.221–0.489	<0.001
(ii) multivariate analysis
IMT (mm)	0.241	0.078–0.405	0.004
Suita score	2.994	1.662–4.326	<0.001
CAC	0.139	0.057–0.221	0001
AAC grade	0.265	0.127–0.404	<0.001

Dependent variable: IMT, suita score, CAC, and AAC grade; independent variables: FIB4 index adjusted for diastolic blood pressure, eGFR, and HbA1c. FIB4 index, fibrosis-4 index; IMT, intima-media thickness; CAC, carotid artery calcification; AAC, aortic artery calcification; eGFR, estimated glomerular filtration rate; HbA1c, glycosylated hemoglobin.