Intensive Blood Pressure Control and Diabetes Mellitus Incidence for Patients with Impaired Fasting Glucose: A Secondary Analysis of SPRINT
Table 1
Baseline characteristics of study participants.
Characteristics
Overall
Standard BP control
Intensive BP control
value
N = 3310
N = 1651
N = 1659
Age
67 (61, 75)
67 (61, 75)
67 (61, 75)
0.8
Gender (female)
962 (29%)
494 (30%)
468 (28%)
0.3
BMI (kg/m^2)
29.9 (26.9, 33.7)
29.8 (27.0, 33.5)
29.9 (26.7, 34.0)
0.9
SBP (mmHg)
138 (129, 148)
138 (129, 148)
137 (129, 148)
0.5
DBP (mmHg)
78 (70, 86)
77 (70, 86)
78 (70, 85)
0.6
SBP tertile
<132 mm·Hg
1,166 (35%)
560 (34%)
606 (37%)
0.2
132−145 mm·Hg
1,079 (33%)
558 (34%)
521 (31%)
>145 mm·Hg
1,065 (32%)
533 (32%)
532 (32%)
FRS (≥15%)
2,156 (65%)
1,075 (65%)
1,081 (65%)
>0.9
Race (black)
855 (26%)
429 (26%)
426 (26%)
0.8
Number of antihypertensive agents
<2
1,191 (36%)
604 (37%)
587 (35%)
0.5
≥2
2,119 (64%)
1,047 (63%)
1,072 (65%)
Aspirin
1,774 (54%)
867 (53%)
907 (55%)
0.2
Smoking status
Never smoked
1,428 (43%)
722 (44%)
706 (43%)
0.8
Former smoker
1,515 (46%)
741 (45%)
774 (47%)
Current smoker
365 (11%)
187 (11%)
178 (11%)
Missing data
2 (<0.1%)
1 (<0.1%)
1 (<0.1%)
Baseline CKD
892 (27%)
457 (28%)
435 (26%)
0.3
Previous CVD
683 (21%)
337 (20%)
346 (21%)
0.8
eGFR (ml/min/1.73 m2)
72 (59, 85)
71 (58, 85)
73 (59, 85)
0.3
Serum creatinine (mg/dL)
1.01 (0.87, 1.20)
1.03 (0.86, 1.21)
1.00 (0.87, 1.20)
0.4
CHR (mg/dL)
184 (159, 212)
185 (160, 214)
184 (158, 211)
0.1
GLUR (mg/dL)
106 (102, 112)
106 (102, 111)
106 (102, 112)
0.12
HDL (mg/dL)
48 (41, 57)
48 (41, 57)
48 (41, 57)
0.4
TRR (mg/dL)
115 (83, 163)
114 (82, 162)
115 (84, 164)
0.9
Urine albumin-to-creatinine ratio (mg/g)
9 (6, 21)
9 (5, 22)
10 (6, 20)
0.7
Data were expressed as median (interquartile range) or number (percentage); BP: blood pressure; BMI: body mass index; SBP: systolic blood pressure; DBP: diastolic blood pressure; FRS: Framingham risk score; CKD: chronic kidney disease; CVD: cardiovascular disease; eGFR: estimated glomerular filtration rates; CHR: cholesterol; GLUR: glucose; HDL: high density lipoprotein cholesterol direct; TRR: triglycerides; to convert the values for creatinine to micromoles per liter, multiply by 88.4. To convert the values for cholesterol to millimoles per liter, multiply by 0.02586. To convert the values for triglycerides to millimoles per liter, multiply by 0.01129. To convert the values for glucose to millimoles per liter, multiply by 0.05551. Race and ethnic group were self-reported. BMI is the weight in kilograms divided by the square of the height in meters.
