Research Article

Intensive Blood Pressure Control and Diabetes Mellitus Incidence for Patients with Impaired Fasting Glucose: A Secondary Analysis of SPRINT

Table 2

Incident outcome events by two treatment strategies.

Incident T2DStandard BP control
N = 1651
Intensive BP control
N = 1659
value

Median duration of follow-up3.22 years
No. of events256 (16%)293 (18%)0.1
Person time years5189.345151.73
HR (95% CI)Reference1.18 (1.00–1.40)0.052
Incidence rate per 1000 person-years of treatment strategy (95% CI)49.33 (43.29, 55.37)56.87 (50.36, 63.39)

Incident IFGRN = 1395N = 1366

Median duration of follow-up2.98 years
No. of events632 (45%)559 (41%)0.02
Person time years3994.993958.85
HR (95% CI)Reference0.9 (0.8–1.01)0.067
Incidence rate per 1000 person-years of treatment strategy (95% CI)158.20 (145.86, 170.53)141.20 (129.50, 152.91)

T2D: type 2 diabetes; IFGR: impaired fasting glucose reversion; BP: blood pressure; HR: hazard ratio; CI: confidence interval.