Development of an Inflammation-Associated Colorectal Cancer Model and Its Application for Research on Carcinogenesis and Chemoprevention
Figure 15
Mutations in the GSK-3β phosphorylation consensus motif of the β-catenin gene in adenocarcinomas of mice induced by AOM/DSS, DMH/DSS, PhIP/DSS, and 2-amino-3,8-dimethylimidazo-[4,5-f]-quinoxaline (MeIQx)/DSS. PhIP and MeIQx are heterocyclic amines.