Development of an Inflammation-Associated Colorectal Cancer Model and Its Application for Research on Carcinogenesis and Chemoprevention
Figure 9
Inflammation and nitrotyrosine-positive scores in the colon of mice that received AOM and/or DSS (0.1%, 0.25%, 0.5%, 1%, or 2% DSS in drinking water). (a) Significantly different: a , versus AOM0.5% DSS group; b , versus AOM0.1% DSS group; c and d , versus AOM alone group; e , versus 2% DSS alone group; and f , g , h , and i , versus no treatment group. (b) Significantly different: a , versus AOM0.5% DSS group; b and c , versus AOM0.25% DSS group; d and e , versus AOM0.1% DSS group; f and g , versus AOM alone group; h , versus 2% DSS alone group; and i and j , versus no treatment group.
