Development of an Inflammation-Associated Colorectal Cancer Model and Its Application for Research on Carcinogenesis and Chemoprevention

Table 1

Inflammation and cancer in various tissues.

Chronic inflammation	Site and associated cancer
Chewing tobacco, Oral irritation	Oral squamous cell carcinoma
Smoking, Chronic bronchitis, Chronic	Lung cancer
obstructive pulmonary disease
Asbestosis	Mesothelioma
Reflux esophagitis, Barrett’s esophagus	Esophageal adenocarcinoma
H. pylori-induced gastritis	Gastric cancer, Mucosa-associated lymphoid tissue lymphoma
Chronic pancreatitis	Pancreatic adenocarcinoma
Viral (Hepatitis B and C virus) hepatitis	Hepatocellular carcinoma
Opisthorchis sinensis infection (liver fluke)	Cholangio carcinoma
Inflammatory bowel disease (IBD)	Colorectal adenocarcinoma
Pelvic inflammatory disease	Ovarian cancer
Human papilloma virus (HPV) infection	Anogenital carcinoma
Schistosomiasis	Bladder cancer
Chronic scar tissue	Scar cancer arising in pre-existing scars in the lung, skin, and other tissues
Human herpes simplex virus type 8	Kaposi sarcoma
Chronic oesteomyelitis	Osteosarcoma