Review Article
OMICS Approaches Evaluating Keloid and Hypertrophic Scars
Table 3
Gene association for keloid and hypertrophic scars in different populations.
| Gene association | Observations |
| Codons 10, 25, and 263 and for −509 and −800 single nucleotide polymorphisms of the TGF-β1 gene | Keloid/HTS patients and controls for codons were not statistically significant for genotype or allele occurrence [51] | Region rs873549 on chromosome 1q41 | Keloid only [56]. | rs1511412 at 3q22.3 | Keloid only. LOC389151, a hypothetical gene located 24 kb telomeric to rs1511412, and FOXL2 gene association [56]. | rs8032158 at 15p21.3 | Keloid only. NEDD4 gene association [56]. | HLA-DRB104, 09, 12 and 15. HLA-DRB115 | Predisposition to keloids [60] |
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