In Vitro and In Vivo Anti-Inflammatory Properties of the Hydroethanolic Extract of the Roots of Vernonia guineensis (Asteraceae)
Table 4
Effect of the hydroethanolic extract of V. guineensis on hematology.
Treatment
Dose (mg/kg)
White blood cells (103/µl)
Red blood cells (106/µL)
Hemoglobins (g/dl)
Hematocrit (%)
Platelets (109/L)
Normal control
—
5.64 ± 0.44
5.50 ± 0.31
13.90 ± 0.36
50.15 ± 4.45
292.40 ± 29.74
Negative control
—
11.46 ± 0.69λ
3.25 ± 0.15λ
10.14 ± 0.31λ
43.72 ± 0.93
394.20 ± 11.28β
Diclofenac
5
9.64 ± 0.55λ
3.42 ± 0.24λ
11.56 ± 0.48α
46.14 ± 1.62
328.80 ± 9.62
HEE
62.5
8.66 ± 0.30λb
3.63 ± 0.22λ
9.44 ± 0.68λ
37.24 ± 1.79β
372.40 ± 10.30α
125
7.70 ± 0.36c
4.37 ± 0.11αa
11.92 ± 0.67
42.56 ± 2.56
328.00 ± 14.08
250
5.88 ± 0.12c
5.29 ± 0.18c
13.68 ± 0.35c
50.12 ± 0.92
298.80 ± 22.86a
Each value represents the mean ± standard error on the mean of 5 animals and analyzed by one-way ANOVA followed by Tukey’s post test. a,b and c compared with the negative control and α,β, and λ compared with the neutral control.