|
| Function and gene | Description | Logarithmic ratio (S/C) | P-value |
|
| Amino acid biosynthesis | | | |
| hisG | Histidine biosynthesis | 2.05 | - |
| argB | Arginine biosynthesis | 3.05 | - |
| argC | Arginine biosynthesis | 3.52 | - |
| argG | Arginine biosynthesis | 3.07 | - |
| asnB | Asparagine synthetase B | 3.41 | - |
| thrL | Thr operon leader peptide | 3.43 | - |
| cysK | Cysteine biosynthesis | 3.53 | - |
|
| Antibiotic resistance | | | |
| marA | Multiple antibiotic resistance protein | 4.20 | - |
| marB | Multiple antibiotic resistance protein | 4.41 | - |
| marR | Multiple antibiotic resistance protein | 5.16 | - |
|
| DNA replication/repair, restriction/modification | | | |
| priB | Primosomal replication protein | 2.19 | - |
| topA | DNA topoisomerase I | 2.33 | - |
| fis | DNA binding protein Fis | 2.37 | - |
| priA | Primosome assembly protein | 2.60 | - |
|
| Metabolism | | | |
| aceE | Pyruvate dehydrogenase E1 subunit | 2.03 | - |
| asmA | Protein asmA precursor; electron transport | 2.21 | - |
| lpdA | Dihydrolipoamide dehydrogenase; energy metabolism | 2.24 | - |
| nemA | N-ethylmaleimide reductase; central intermediary metabolism | 2.71 | - |
| glpC | Anaerobic glycerol-3-phosphate dehydrogenase subunit C | 2.81 | - |
| yfhO | Cysteine metabolism; amino acid metabolism | 3.25 | - |
| icdA | Isocitrate dehydrogenase; TCA cycle metabolism | 3.48 | - |
| adhC | Alcohol dehydrogenase class III; energy metabolism | 4.19 | - |
| yibO | Phosphoglyceromutase; carbohydrate metabolism | 6.21 | - |
| ttdB | L(+)-tartrate dehydrase; energy metabolism | 0.44 | - |
| hycG | Formate hydrogenlyase subunit 7; mitochondrial electron transport | 0.44 | - |
| phnH | Carbon-phosphorus lyase complex subunit; central intermediary metabolism | 0.45 | - |
| mhpF | Acetaldehyde dehydrogenase; amino acid metabolism | 0.46 | - |
| phnJ | Carbon-phosphorus lyase complex subunit; central intermediary metabolism | 0.46 | - |
| hycF | Hydrogenase 4 Fe-S subunit formate hydrogenlyase, complex iron-sulfur protein | 0.47 | - |
| eutI | Phosphate acetyltransferase | 0.47 | - |
| ygjL | 2,4-dienoyl-CoA reductase (NADPH), NADH and FMN-linked | 0.49 | - |
|
| Pathogenesis and virulence | | | |
| vacB | Ribonuclease R, exoribonuclease R, RNase R | 2.26 | - |
| tolA | Colicin production | 2.26 | - |
| wcaL | Colanic acid biosynthesis; resistance to acid stress, desiccation, and thermal stress | 2.51 | - |
| ygeO | Hypothetical protein | 2.66 | - |
|
| Phage, transposon, or plasmid | | | |
| sieB | Rac prophage; phage superinfection exclusion protein | 0.43 | - |
| Lar | Rac prophage; restriction alleviation protein | 0.43 | - |
| ydaE | Rac prophage; conserved protein | 0.44 | - |
| ydaQ | Rac prophase; conserved protein | 0.45 | - |
| ydaC | Rac prophage predicted protein | 0.50 | - |
| ymfP | E14 prophage; conserved protein | 4.46 | - |
| mprA | Translational repressor mprA; plasmid related function | 3.53 | - |
|
| Ribosomal proteins | | | |
| rpsU | 30S ribosomal protein S21 | 2.25 | - |
| rpsT | 30S ribosomal protein S20 | 2.35 | - |
| rplY | 50S ribosomal protein L25 | 2.35 | - |
| rpmF | 50S ribosomal protein L32 | 2.43 | - |
| rpmH | 50S ribosomal protein L34 | 2.52 | - |
| rplK | 50S ribosomal protein L11 | 2.67 | - |
| rpsR | 30S ribosomal protein S18 | 2.87 | - |
| rplA | 50S ribosomal protein L1 | 2.87 | - |
| rpmD | 50S ribosomal protein L30 | 3.17 | - |
| rpsJ | 30S ribosomal protein S10 | 3.24 | - |
| rpmE | 50S ribosomal protein L31 | 3.32 | - |
| rplW | 50S ribosomal protein L23 | 3.53 | - |
| rpsH | 30S ribosomal protein S8 | 4.34 | - |
| rplF | 50S ribosomal protein L6 | 4.57 | - |
| rplX | 50S ribosomal protein L24 | 4.66 | - |
| rpsN | 30S ribosomal protein S14 | 5.68 | - |
|
| Stress response | | | |
| cspE | Cold shock protein E | 2.02 | - |
| yfiA | Cold shock protein, associated with 30S ribosomal subunit | 2.10 | - |
| htpX | Heat shock protein | 2.10 | - |
| sulA | SOS cell division inhibitor | 2.17 | - |
| ymcE | Cold shock gene | 2.33 | - |
| dnaK | Heat shock protein; molecular chaperone | 2.48 | - |
| recA | Recombinase A; SOS response | 2.59 | - |
| rpoS | Response to organic acid stress and acetate induced acid tolerance; regulatory function | 2.68 | - |
| ahpC | Alkyl hydroperoxide reductase C22 protein; oxidative stress | 2.91 | - |
| dead | Cold shock DEAD box protein A | 3.04 | - |
| rpoH | RNA polymerase sigma factor; heat response | 3.19 | - |
| Spy | Envelope stress induced periplasmic protein | 3.54 | - |
| osmB | Osmotic adaptation; Osmotically inducible lipoprotein B precursor | 4.77 | - |
| cspG | Cold shock protein | 5.04 | - |
| cpxP | Envelope stress response | 7.08 | - |
| cspA | Cold shock protein cspA, major cold shock protein | 8.59 | - |
|
| Transcription, RNA processing, and degradation | | | |
| rpoB | DNA directed RNA polymerase beta subunit; transcription | 2.12 | - |
| rpoD | Hypothetical protein, RNA polymerase sigma factor | 2.20 | - |
| Pnp | Polyribonucleotide, nucleotidyltransferase; RNA processing | 2.21 | - |
| rpnA | Ribonuclease P | 2.31 | - |
| Rne | Ribonuclease E, fused ribonuclease E: endoribonuclease | 2.72 | - |
| rpoA | DNA-directed RNA polymerase alpha subunit; transcription | 2.92 | - |
| nusA | Transcription elongation factor NusA | 3.16 | - |
| Rho | Transcription termination factor Rho | 3.34 | - |
|
| Translation and posttranslational modification | | | |
| soxS | Regulatory protein, DNA binding dual transcriptional regulator | 2.44 | - |
| tufA | Elongation factor Tu, protein chain elongation factor (EF-Tu) | 2.61 | - |
| infA | Translation initiation factor IF-1 | 3.09 | - |
| infC | Translation initiation factor IF-3 | 3.31 | - |
| fusA | Elongation factor EF-2 | 3.36 | - |
| infB | Translation initiation factor IF-2 | 4.13 | - |
|
| Transport and binding proteins | | | |
| phnO | Phosphonate transport, N-acetyltransferase activity | 0.46 | - |
| treB | PTS system, trehalose-specific IIBC component; transport of small molecules | 0.47 | - |
| malK | Maltose/maltodextrin transport | 0.48 | - |
| thiQ | Thiamine transport | 0.49 | - |
| fepB | Iron-enterobactin transporter subunit | 0.49 | - |
| cusB | Copper efflux system protein | 2.02 | - |
| yjbB | Phosphate transport, sodium dependent phosphate transporter | 2.07 | - |
| livJ | Leucine/isoleucine/valine transporter subunit | 2.22 | - |
| oppA | Oligopeptide transporter subunit | 2.32 | - |
| lolE | Lipoprotein releasing system, transmembrane protein lolE | 2.32 | - |
| prlA | Preprotein translocase; protein transport | 2.46 | - |
| glnH | Glutamine ABC transporter, periplasmic-binding protein | 2.50 | - |
| artP | Arginine transport | 2.52 | - |
| fepD | Ferric enterobactin transport system | 3.25 | - |
| fepE | Ferric enterobactin transport protein | 3.85 | - |
|
