Review Article
Antipseudomonal β-Lactams Resistance in Iran
Table 2
Mechanisms of β-lactams resistance (except Ambler class A-associated genes).
| | Resistance genes | Number of studies | Number of Pseudomonas evaluated for resistance genes | Number of genes responsible for beta-lactam resistance |
| | ESBL encoding genes | | | | | blaOXA | 2 | 140 | 34 | | blaOXA-1 | 4 | 472 | 79 | | blaOXA-4 | 3 | 267 | 34 | | blaOXA-10 | 8 | 542 | 329 | | blaOXA-48 | 1 | 53 | 0 |
| | AmpC encoding | | | | | AmpC ∗ | 9 | 610 | 478 |
| | MBL encoding genes | | | | | blaIMP | 11 | 833 | 226 | | blaIMP-1 | 7 | 977 | 139 | | blaIMP-2 | 2 | 539 | 11 | | blaVIM | 14 | 797 | 98 | | blaVIM-1 | 5 | 916 | 146 | | blaVIM-2 | 6 | 730 | 11 | | blaNDM | 5 | 470 | 0 |
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∗One study was associated with oprD, and 56.5% was oprD downregulation.
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